Supervisor: Shodimu -Emmanuel Olufemi R. 313
Lab Research Goals:
There are two parts to our research emphasis: The first part of our research involves cloning, expression, validation and of microRNAs (miRNAs) in mammalian cell lines. One of the goals is to determine by experiments the of on mRNAs genes that regulate cell cycle, alternative splicing, program cell death and survival. In general, inadequate regulation of of the three areas of interest can be detrimental to cells
The second part of our research involves analyzing the effects of toxins and toxicants on expression of miRNAs that either up- or down-regulate before and after exposure; and determine their effects on cell cycle, alternative splicing, program cell death and survival, while simultaneously analyzing the cell morphological changes as well.