Department of Immunology – The University of Texas MD Anderson Cancer Center, Houston, TX 2005 2007
Department of Experimental Pediatrics – The University of Texas MD Anderson Cancer Center Houston, TX 2007 2011
HONORS AND AWARDS:
University Academic Scholarship Prairie View A&M University, 1987
Premedical Concepts Institute Scholarship Prairie View A&M University, 1987
Department of Biology Scholar Prairie View A&M University, 1992
EPA Predoctoral Fellowship, $75,000, 1997-2000
National Heart, Lung and Blood Institute (NHLBI) traineeship recipient (did not accept), 2001
Whos Who Among Americas Teachers, 2001
National Heart, Lung and Blood Institute (NHLBI) Postdoctoral Fellowship, 2005
National Cancer Institute (NCI) Postdoctoral Fellowship, 2007
Mike Doiron Memorial 19th Annual Legends of Friendswood Education Foundation Award, The University of Texas M. D. Anderson Cancer Center and The Legends of Friendswood Education Foundation, $15,000, 2008
National Cancer Institute (NCI) Postdoctoral Fellowship, 2010
PROFESSIONAL MEMBERSHIPS:
American College of Toxicology (ACT)
Beta Kappa Chi National Scientific Honor Society
Society of Environmental Toxicology and Chemistry (SETAC)
National Organization for the Professional Advancement of Black Chemists and Chemical Engineers (NOBCChE)
Research/Scholarly Activities
SDS-PAGE
Immunohistochemistry
Spectrophotometry
Immunoprecipitation
ELISA
Immunofluorescence
Flow cytometry/FACS analysis
Cell death assays
Cell culture
Cell isolation and purification
Generation of plasmid DNA
DNA and RNA purification
Experimental design preparation
Animal care and genotyping
Polymerase Chain Reaction (PCR)
Bacterial transformation
Cell transfection and transduction
Primary cell line generation
Murine bone marrow transplant
Murine embryo harvesting and dissection
Animal handling and dissection
Numerous other standard laboratory techniques
Recent Publications (out of a total of xxx)
Yu L, Su B, Hollomon M, Facchinetti V, Zhou Z, Kleinerman E. The use of MEKK3 knockout bone marrow cells to demonstrate the essential role of vasculogenesis in Ewings sarcoma growth. Cancer Res 2010, 70:1334-1343.
Huang G, Yu L, Cooper L, Hollomon M, Huls H, Kleinerman E. Genetically modified T cells targeting interleukin-11 receptor I^+–chain kill human osteosarcoma cells and induce the regression of established osteosarcoma lung metastases. Cancer Res 2012, 72(1):271-281.
Hollomon M,1,2 Santiago-OFarrill JM,1 Kleinerman E.1 Knockdown of essential protein, ATG5, decreases oxidative stress and has an opposing effect on camptothecin-induced cytotoxicity in osteosarcoma cells. [submitted under review (abstract available for preview)]
1Childrens Cancer Hospital of MD Anderson Cancer Center, Houston, TX
2 Texas Southern University, Department of Biology, Houston, TX
Hollomon M,1,2 Zhou Z,1 Santiago-OFarrill JM,1 Gordon N,1 Kleinerman E.1 Fas-associated protein with Death Domain (FADD) knockdown sensitizes osteosarcoma to TNF-induced cell death. [submitted under review (abstract available for preview)] 1Childrens Cancer Hospital of MD Anderson Cancer Center, Houston, TX
2 Texas Southern University, Department of Biology, Houston, TX
Nishimoto K,1 Yang Y,1 Hollomon M,1,2 Bernard V, Hughes D,1 Kleinerman E.1 MS-275 increases Fas expression on osteosarcoma cells by a mechanism involving the microRNA-17-92 cluster and E2F1 transcription. [expected submission in August]
1Childrens Cancer Hospital of MD Anderson Cancer Center, Houston, TX
2 Texas Southern University, Department of Biology, Houston, TX
Gordon, N,1 Hsuan-Chu C,1 Santiago OFarrell, J,1 Gilbert, B,1 Hollomon, M,1,2 Kleinerman, E.1 The microenvironment plays an important role in the ability of aerosol Liposomal
9-Nitorcamptothecin and Gemcitabine to elicit therapeutic effect on Osteosarcoma lung metastases. [in preparation]
1Childrens Cancer Hospital of MD Anderson Cancer Center, Houston, TX
2 Texas Southern University, Department of Biology, Houston, TX
ABSTRACTS AND OTHER PRESENTATIONS:
Department of Experimental Pediatrics, The University of Texas MD Anderson Cancer Center, 9-nitrocamptothecin-induced Autophagy in Osteosarcoma Cells March 18, 2008
Autophagy in Health and Disease: A Workshop on Cross-Disciplinary Issues, The University of Texas Medical School at Houston, Camptothecin-induced Autophagy November 14, 2008
Department of Cancer Biology Seminar Series, The University of Texas MD Anderson Cancer Center, 9-nitrocamptothecin-induced Autophagy in Osteosarcoma Cells January 21, 2009
Department of Experimental Pediatrics, The University of Texas MD Anderson Cancer Center, Autophagy Induction in Osteosarcoma May 12, 2009
Department of Experimental Pediatrics, The University of Texas MD Anderson Cancer Center, Drug-induced Autophagy in Osteosarcoma March 9, 2010
Funding
Texas Southern University – University Seed Grant
Hogan (PI) Hollomon (Co-PI), 2003
[grant written by Hollomon]
National Heart Lung and Blood Institute (National Institutes of Health)
Research supplement grant 7R011HL070225-03S1 (PI- Su)
Funds awarded to support Postdoctoral studies for Mario Hollomon, Ph.D.
(2005-2007, $119,596)
[grant written by Su]
National Cancer Institute (National Institutes of Health)
Research supplement grant 5R01CA042992-22S1 (PI Kleinerman)
Funds awarded to support Postdoctoral studies for Mario Hollomon, Ph.D.
(2007-2009, $213,803)
[grant written by Hollomon]
National Cancer Institute (National Institutes of Health)
Research supplement grant 5R01CA042992-24S1 (PI Kleinerman)
Funds awarded to support Postdoctoral studies for Mario Hollomon, Ph.D.
(2010-2011, $92,714)
[grant written by Hollomon]
