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Biographical Information
September 27, 2023
Location: SB 156
Time: 12:00 pm
Presenter: Dr. Tuan Phan
Ruthenium Complexes: A Promising Alternative to Platinum-Based Compounds in Medicinal Chemistry
Abstract: In the late 1960s, scientists at Michigan State University discovered cisplatin’s potential as an anti-cancer treatment while studying bacterial cell development under electric fields. This marked a new era in metal-based chemotherapy research. Despite effective platinum-based cancer treatments, limitations like drug resistance and side effects have spurred research for alternative metal-based anti-cancer agents. Ruthenium compounds, particularly known for forming octahedral complexes, have garnered attention. Yet no ruthenium complex is approved for therapeutic use. The Phan Lab at TSU focuses on creating robust, reactive, selective, and soluble ruthenium complexes for challenging conditions.
Tuan Phan holds the position of chemistry professor at Texas Southern University. He earned his Ph.D. in organic chemistry from the University of Houston. His research pursuits encompass two primary areas: ruthenium complexes and environmental chemistry. He has served as a research advisor for the Ph.D. in Environmental Toxicology and Master of Chemistry programs. In addition, he has served as a research mentor to many undergraduate students.
Feb. 21, 2018, 12:00 pm, SB 303H SB
“Supermolecular Inorganic Chemistry and Reduction of Carbon Dioxide”
by
Dr. Andrew Maverick
Associate Dean
Department of Chemistry
Louisiana State University.
Please click to download the flyer.
Michigan State University Department of Chemistry Excellence-in-Teaching Citation, 1975
Briargate Civic Club Distinguished Service Award, 1978
Briargate Community Citizen of the Year Award, 1980
Briargate Civic Club Distinguished Service Award, 1980
Marquis Who’s Who in Frontier Science and Technology, 1982
Kappa Alpha Psi Distinguished Service Award, 1982
Kappa Alpha Psi Achievement Award, 1983
Alpha Kappa Alpha Sorority Community Service Award, 1983
National Organization of Black Chemists and Chemical Engineers Appreciation Award, 1984
Houston Alumni Chapter of Kappa Alpha Psi Fraternity 1984 Spotlight Award Who’s Who in Texas, 1985
National Organization of Black Chemists and Chemical Engineers Outstanding Teacher Award, 1985
Ruby W. Hilliard Memorial Professional Achievement Award, 1985
Who’s Who Among Black Americans, 1987
“Albert Einstein” World Award of Science Diploma, 1987
Fellow, The American Institute of Chemists, 1988
Texas Southern University Researcher of the Year, 1988
Kappa Alpha Psi Distinguished Service Award, 1988
Kappa Alpha Psi Southwest Province Graduate Brother of the Year Award, 1988
First White House Initiative Faculty Award for Excellence in Science and Technology, 1988
The Audrey Logan Citizenship Award, 1988
Texas Southern University Program Council’s “Showcase” of Black Talent Award, 1989
Texas Southern University’s College of Arts & Sciences Outstanding Teacher Award, 1989
Texas Southern University’s McCleary Teacher of the Year Award, 1989
Briarchase Baptist Church Outstanding Black Achiever Award, 1990
Fort Bend County Commissioner’s Distinguished Service Award, 1989
Houston’s Mystic Knights, Man of the Year, 1990
Fellow, Texas Academy of Science, 1991
Sigma Gamma Rho Sorority, Men on the Move in the 90’s Award, 1992
Texas Justice Court Certificate of Special Recognition, 1992
Texas Court of Criminal Appeals Certificate of Appreciation, 1992
Who’s Who in American Education, 1992
Who’s Who Worldwide, 1992
National Organization for the Professional Advancement of Black Chemists and Chemical Engineers Appreciation Award, 1993
National Technical Association Scientist of the Year Award, 1993
Texas Southern University’s Ocean of Soul “Back in Stride” Award, 1993
Gulf Coast Chapter of the National Organization for the Professional Advancement of Black Chemists and Chemical Engineers Appreciation Award, 1994
Listed Among American Men and Women of Science, 1994
Briarchase Baptist Church Man of the Year Award, 1996
Alabama State University Alumni of Distinction Award, 1997
Listed Among American Men and Women of Science, 1997
Houston Alumni Chapter of Kappa Alpha Psi Fraternity Cleveland B. Davis Kappa Achiever Award, 1999
Texas Southern University Student Support Services Award, 2001
Texas Southern University Student Support Services Award, 2002
University of Houston Downtown Salute, 2002
Houston League of Business and Professional Women Ombudsmen Men of Valor and Achievement Award, 2002
Kappa Alpha Psi, Laurel Wreath Recipient, 2005
Fellow, African Scientific Institute, 2006
Texas Southern University, Missouri City Links, STEM-ulating College for a Day Award, 2009
Minority Access Mentor Award, 2009
Texas Southern University, Missouri City Links, STEM-ulating College for a Day Award, 2010
Texas Southern University, College of Science and Technology, Leadership Award, 2011
Texas Southern University, Missouri City Links, STEM-ulating College for a Day Award, 2011
Fellow, American Chemical Society, Since 2011
Texas Southern University, College of Science and Technology, Leadership Award, 2011
Texas Southern University, Missouri City Links, STEM-ulating College for a Day Award, 2011
American Association for the Advancement of Science (AAAS) Mentor Award for Lifetime Achievement, 2011
Michigan State Universitys College of Natural Science, Outstanding Alumni Award, 2012
College of Science and Technology Undergraduate Advisor/Mentoring Award, 2012
Texas Southern University Presidential Achievement Medal Award, 2012
Texas Southern University, College of Science and Technology, Distinguished Service Award, 2013
Texas Southern University, University Distinguished Service Award, 2013
BEYA STEM Black Engineer Promotion of Education Award, 2013
After graduating from R.E. Hunts High School, Columbus Mississippi in 1962, Dr. Bobby L. Wilson went on to earn a BS degree in Chemistry from Alabama State University in 1966 and the MS degree in Chemistry from Southern University in 1972. He culminated his academic training by taking a Ph.D. degree in Chemistry from Michigan State University in 1976.
Dr. Wilson has distinguished himself as a professor, scientist and an administrator. Since 1976, Wilson has been employed at Texas Southern University in many capacities. Currently, Dr. Wilson is L. Lloyd Woods Distinguished Professor of Chemistry and Shell Oil Endowed Chaired Professor of Environmental Toxicology after serving as Acting President, Provost, L. Lloyd Woods Distinguished Professor of Chemistry and Shell Oil Endowed Chaired Professor of Environmental Toxicology (4/2006-2/2008); Provost and L. Lloyd Woods Distinguished Professor of Chemistry and Shell Oil Endowed Chaired Professor of Environmental Toxicology (8/2004-4/2006); Provost and L. Lloyd Woods Distinguished Professor of Chemistry (9/2001-8/2004); Provost and Professor of Chemistry (10/1999-9/2001); Professor and Chair of Chemistry (9/1997-10/1999); on assignment as Program Director, National Science Foundation, Washington, D.C. (2/1996-9/1997); Professor and Chair of Chemistry (9/1995-2/1996); Professor of Chemistry (1/1994-9/1995); Provost and Professor of Chemistry (1/1992-1/1994); Vice President of Academic Affairs and Professor of Chemistry (6/1990-1/1992); Professor and Head of Chemistry (9/1987-9/1989); Associate Dean, College of Arts and Sciences and Professor of Chemistry (9/1986-9/1987); Professor of Chemistry (9/1985-9/1986); Associate Professor of Chemistry (9/1983-9/1985); on assignment as Visiting Research Professor, Exxon Research and Engineering Company, Baytown, TX (6/1982-9/1983; Associate Professor of Chemistry (1980-1982); and Assistant Professor of Chemistry (1976-1980).
Wilson also served as a Graduate Teaching Assistant, Michigan State University, East Lansing, MI (9/1971-6/1976), Science Teacher, Booker T. Washington High School, Montgomery, AL (9/1966-1970), and Science Teacher, Jefferson Davis High School, Montgomery, AL (1970-1971).
Dr. Wilsons administrative accomplishments at Texas Southern University are highlighted through the following: (1) programs enhanced and created to equip students to surpass the requirements of academic and professional proficiency measures, (2) identification of resources to strengthen administrative, faculty, and staff initiatives, (3) promotion of campus outreach programs in the community and surrounding public schools, and (4) productive representation of the institution with public officials.
He has been a driving force in shaping academic science programs nationally. He has also served as a program director at the National Science Foundation. He holds memberships in numerous professional organizations. Dr. Wilson is a member of the Texas Academy of Science (fellow), the American Chemical Society (fellow), the African Scientific Institute (fellow), Sigma XI (fellow), and is the Chair of the Executive Board of the National Organization of Black Chemists and Chemical Engineers (NOBCChE). His combination of discipline, experience, and command of his subject area has enabled him to produce over seventy publications in scientific journals and books. He holds two patents with one pending and is listed in several Whos Who publications. Other honors include the NOBCChE Outstanding Teacher Award, 1985; Texas Southern University Researcher of the Year, 1988; First White House Initiative Faculty Award for Excellence in Science and Technology, 1988; Texas Southern Universitys Teacher of the Year Award, 1989; National Technical Association Scientist of the Year Award, 1993; Alabama State University Alumni of Distinction Award, 1997; Kappa Alpha Psi Fraternity, Inc., Laurel Wreath Recipient, 2005; Texas Southern University, Missouri City Links, STEM-ulating College for a Day Award, 2009; Minority Access Mentor Award, 2009; Texas Southern University, Missouri City Links, STEM-ulating College for a Day Award, 2010; Texas Southern University, College of Science and Technology, Leadership Award, 2011; Texas Southern University, Missouri City Links, STEM-ulating College for a Day Award, 2011; American Association for the Advancement of Science (AAAS) mentor Award for Lifetime Achievement, 2012; Michigan State Universitys College of Natural Science, Outstanding Alumni Award, 2012; Texas Southern University, College of Science and Technology Undergraduate Advisor/Mentor Award, 2012; Texas Southern University, Presidential Achievement Medal Award, 2012; Texas Southern University, University Distinguished Service Award, 2013; and BEYA STEM Black Engineer Promotion of Education Award, 2013.
Perhaps his most ambitious and forward-looking venture has been his efforts to help in the establishment of the Louis Stokes Alliance for Minority Participation (LSAMP) in seven Houston-area colleges and universities. He is the co-principal investigator of this consortium, which is designed to substantially increase the number of underrepresented minorities in the fields of science, technology, engineering, and mathematics (STEM). The programs success in producing STEM graduates has earned it the title of Crown Jewel of the National Science Foundations. Its success at Texas Southern University and other Houston-area colleges and universities has been judged to be among the best LSAMP program in the nation. This judgment bears witness to Dr. Wilsons vision and leadership.
Not only is Dr. Wilson nationally known for his remarkable scholarly achievements and publications, he has also been a mentor to over 70 MS degree students in Chemistry and 25 MS and/or Ph.D. degree students in Environmental Toxicology. Wilson was instrumental in establishing the Environmental Toxicology Program as Texas Southern Universitys first Ph.D. program in 1994. Dr. Wilson has also been instrumental in building the research component of the science programs at Texas Southern University. His efforts have generated over 100 million in research and training grants for the university.
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Akhter, Asma, (Advisor: B.L. Wilson), Measuring The Trace Metals (Mo, Cd, Sn, U, and Pb) In Drinking Water From The Houston Area By Inductively Coupled Plasma Mass Spectroscopy (ICP-MS), Texas Southern University, 2013
Tarver, Siobhan, (Advisor: B.L. Wilson), Correlating Biological and Environmental Monitoring Assessing the Risk of Human Exposure to Volatile Organic Compounds in the Greater Houston Area, Ph.D., Texas Southern University, 2013
Lyons, L., (Advisor: B.L. Wilson), Study of In Vivo Exposure of Single-Walled Carbon Nanotubes on Mouse Liver, Ph.D., Texas Southern University, 2011
Ramadi, M., (Advisor: B.L. Wilson), The Study of Nanomaterials and their Antimicrobial Activity, Ph.D., Texas Southern University, 2009
Oyewole, A., (Advisor: B.L. Wilson) Toxicological Evaluation of SelectedHouston Area Aquatic Systems, Ph.D., Texas Southern University, 2009
Clement, J.Q., Lacy, S.M., and Wilson, B.L., Gene Expression Profiling of Human Epidermal Keratinocytes in Simulated Microgravity and Recovery Cultures Geno. Prot. Bioinfo., Vol. 6, No.1, 2008.
Periyakaruppan , A., Sarkar, S., Ravichandran, P., Sadanandan , B., Sharma, C.S, Ramesh , V., Hall, J.C., Thomas, R., Wilson, B.L., and Ramesh, G.T., Uranium induces apoptosis in lung epithelial cells , Arch Toxicology , 2009 June; 83(6) : 595-600.
Prabakaran Ravichandran, Sudhakar Baluchamy, Ramya Gopikrishnan, Santhoshkumar Biradar, Vani Ramesh, Virupaxi Goornavar, Renard Thomas, Bobby L. Wilson, Robert Jeffers, Joseph C. Hall, and Govindarajan T. Ramesh, Pulmonary biocompatibility assessment of inhaled single-wall and multi- wall carbon nanotubes in BALB/C mice, J. Biol. Chem. 2011 jbc.M111.251884. First Published on June 24, 2011, doi:10.1074/jbc.M111.251884.
Keller, R., Bradbury, J., Cramer, R., Erickson, E., Forch, B., Meyer, S., Wilson, B., Disposal Options for the Rocket Motors from Nerve Agent Rockets Stored at Blue Grass Army Depot, National Research Council of the National Academies, Board on Army Science and Technology, International Book Number-13: 978-0-30-26045-9, 2012.
Clemens, P., Wei, X., Wilson, B., Thomas, R., Anatase Titanium Dioxide Coated Single Wall Carbon Nanotubes Manufacture by Sonochemical-Hyrdrothermal Technique, Open Journal of Composite Materials, Vol.3 No. 2A, 2013, pp. 21-32. Dol:10.4236/ojcm.2013.32A004.
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Mr. Daryl F. Wilkerson is currently an Instructor and Laboratory Coordinator of Chemistry at Texas Southern University, with an Masters Thesis, Title: A/ STUDY OF RADIONUCLIDES AS FOUND IN THE AQUEOUS ENVIRONMENT NEAR A COAL FIRED ELECTRIC POWER PLANT/, his research centered on the study of selected radio-nuclides (K-40, U-238, U-235, and Th-232) and their daughter products in the aqueous environment surrounding a coal- fired electric power plant near Houston, Texas. Gamma-ray spectroscopy, consisting of a NaI(TI) scintillation detector, multichannel analyzer and IBM(PC) computer was used in analyzing the samples.
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Nanjing University Materials Chemistry B.S., 1993
Nanjing University Polymer Chemistry and Physics Ph.D., 1998
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Paul Clemens, Xin Wei, Bobby L. Wilson, and Renard L. Thomas, Anatase Titanium Dioxide Coated Single Wall Carbon Nanotubes Manufactured by Sonochemical-Hydrothermal Technique, Open Journal of Composite Materials, 3, 21 (2013)
Isis E. Mejias Carpio, Catherine M. Santos, Xin Wei, and Debora F. Rodrigues, Toxicity of a Polymer-Graphene Oxide Composite against Bacterial Planktonic Cells, Biofilms, and Mammalian Cells, Nanoscale, 4, 4746 (2012).
Jian You, Ruping Shao, Xin Wei, Sanjay Gupta, and Chun Li, Near-Infrared Light Triggers Release of Paclitaxel from Biodegradable Microspheres: Photothermal Effect and Enhanced Antitumor Activity, Small, 6, 1022 (2010).
Merlyn X. Pulikkathara, Oleksandr V. Kuznetsov, Ivana R. G. Peralta, Xin Wei, and Valery N. Khabashesku, Medium Density Polyethylene Composites with Functionalized Carbon Nanotubes, Nanotechnology, 20, 195602 (2009).
Hassan Mahfuz, Mohammad Hasan, Vinod Dhanak, Graham Beamson, Justin Stewart, Vijaya Rangari, Xin Wei, Valery Khabashesku and Shaik Jeelani, Reinforcement of Nylon 6 with Functionalized Silica Nanoparticles for Enhanced Tensile Strength and Modulus, Nanotechnology, 19, 445702 (2008).
Fabrication and Characterization of Advanced Nanocomposite Materials (PI: Dr. Bobby L. Wilson, Co-PIs: Drs. Xin Wei and Renard L. Thomas, Air Force Research Laboratory/Universal Technology Corporation/Clarkson Aerospace Minority Leaders Program, 2005-2013, Total: 1,250,000approx.).
Urban Transportation Environmental Networks (Subproject Co-PI: Lei Yu, Faculty Investigators: Xin Wei, Fengxiang Qiao, and Yi Qi, NSF-CREST, 2011-2016, Subproject Total: $ 1,250,000 approx.).
MRI Consortium: Acquisition of a Small Angle X-ray Scattering System for Materials Characterization (PI: Dr. Ramanan Krishnamoorti, Co-PIs: Drs. Matteo Pasquali, Gila E. Stein, Xin Wei, and Michael Wang, NSF-MRI Program, 2010-2011, Total: $412,772).
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After graduating from Palisade High School (Palisade Charter High School now), Pacific Palisade California in 1984, Dr. Bruce M. Prince went on to earn his BS degree in Chemistry from California State University Bakersfield (CSUB) in 1996. He continued his academic career by earning a Ph.D. degree in Inorganic Chemistry with a specialization in Computational Chemistry from the University of North Texas (UNT) in 2014. Texas Southern University (TSU) has employed Dr. Prince since 2014 as a Research Scientist and as an active Professor of Chemistry. Dr. Prince’s research involves, inorganic chemistry with specialization in computational chemistry, organometallic chemistry, catalyst design. Specific applications Dr. Prince have investigated include: methane-to-methanol (MTM), α-olefin hydroarylation, methane-plus-carbon dioxide to acetic acid, styrene catalysis, C-H bond activation and functionalization, olefin epoxidation, oxidation of metal-alkyl complexes, and C-N bond coupling. This includes chemistry of late transition metals and the main group metals. Dr. Prince career started as a postdoctoral fellow at TSU with Professor Christopher Tymczak, his research was funded through the Centers of Research Excellence in Science and Technology (CREST) and the National Science Foundation (NSF). On the campus of TSU, Dr. Prince is known as a remarkable scholarly instructor of chemistry, which is reflective in his “Rate My Professors” score card. Dr. Prince publications are listed below.
Peer-Reviewed Publications:
1. Substituent Effects of Carbon Dioxide Fixation: A DFT Investigation into the O=C=O bond Cleavage by Three-Coordinate Cobalt (I) Complex Followed by Methane C-H activation-Prince, B. M.; (Manuscript in Completed)
My research focuses on designing novel organometallic catalysts using density functional theory (DFT) and ab initio methods, I have used the correlation consistent Composite Approach (ccCA) developed at UNT. Additionally, I have investigated hydrogen tunneling via nuclear-electronic orbital-MCSCF (NEO-MCSCF) approaches. Specific applications I have investigated include: α-olefin hydroarylation, styrene catalysis, C-H bond activation and functionalization, olefin epoxidation, oxidation of metal-alkyl complexes, C-N bond coupling, and CO2 fixation. Presently, I am a Visiting Assistant Professor at Texas Southern University (TSU) in the Chemistry Department working with the students and continuing my research. In addition, I am currently teaching physical chemistry, the upper division and graduate level inorganic courses.
Field 1, Field 2, Field 3
Title of Ph.D. Dissertation: The Mechanisms of Methane C-H Activation and Oxy-Insertion via Small Transition Metal Complexes: A DFT Computational Investigation
I have participated in groundbreaking and/or novel research that consist of electrochemistry, environmental science and life science research. My research involved 1) investigating the conduction of nanosized metals adhered to modified solid supports, 2) developing nanoscopic electrodes with detection capabilities at trace levels and improve water and soil quality utilizing nanocomposites and 3) modifying solid supports such as textiles and polymers where its functional groups interact with selective biological components. Since, 1994, my research provided experience in analytical chemistry, electrochemistry, surface science, material science, nanoparticles, textile chemistry, agricultural chemistry, biochemistry, environmental chemistry, polymer chemistry and peptide synthesis.
Assessing the East Bay of Galveston Bay, Texas for Coliform Bacteria in Recreational Water, Quach, T.; Colon, L.; Akinrinlola, A.; Bell, J.; Good, S. Open Journal of Marine Science 2016, 6, 472-481
Citrate-Linked Keto- and Aldo-Hexose Monosaccharide Cellulose Conjugates Demonstrate Selective Human Neutrophil Elastase-Lowering Activity in Cotton Dressings, Edwards, Judson V.; Caston, Sonya Journal of Functional Biomaterials, 2013, 4, 59-73
A Bio-Sensor for Human Neutrophil Elastase Employs Peptide-p-Nitroanilide Cellulose Conjugates, Edwards, J. Vincent; Caston, Sonya; Howley, Phyllis; Condon, Brian; Arnold, Judy Sensor Letters, 2008, 6, 4, 518-523
New Uses for Immobilized Enzymes & Substrates on Cotton & Cellulose Fibers, J.Vincent Edwards, Abdul J. Ullah, Kandan Sethumadhavan, Sarah Batiste, Patricia Bel-Berger, Terri Von Hoven, Wilton R. Goynes, Brian Condon, and Sonya Caston , American Chemical Society Symposium Series: Industrial Application of Enzymes on Carbohydrate-Based Material, 2007, 972, 171-185
Detection of Human Neutrophil Elastase with Peptide-Bound Cross-Linked Ethoxylate Acrylate Resin Analogs, Edwards, J. Vincent; Caston, Sonya; Bopp, Alvin F.; and Goynes, Wilton Journal of Peptide Research, 2005, 66, 4, 160-168
2004 Southwest Regional Meeting: “A Systematic Approach to Professional Development”, Caston, Sonya, NOBCChE NEWS OnLine, 2005, 35, 1, 9-11
Characteristics of Nanoscopic Au Band Electrodes, Caston, Sonya L. and McCarley, Robin L. Journal of Electroanalytical Chemistry, 2002, 529, 2, 124-34
X-ray Characterization of Resids from the Wilsonville, Alabama, Two-Stage Direct Liquefaction Facility. 1. XRD and XRF Analysis of the Illinois No. 6 Resids from Run No. 257, Wertz, David L.; Smithhart, Charles B.; and Caston, Sonya Journal of Coal Quality: CQ, 1993, 12, 36
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CONFERENCE PROCEEDINGS PUBLICATIONS:
BOOKS:
PATENTS:
Xin Wei, Yuanjian Deng, Renard L. Thomas, and Bobby L. Wilson,
Instantaneous electrodeposition of metal nanostructures on carbon
nanotubes, filed on December 26, 2007. International patent number
32928/P001WO, pending.
M.S. STUDENTS SUPERVISED:
M.S./Ph.D. THESIS COMMITTEE MEMBER/GRADUATE SCHOOL REPRESENTATIVE:
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Selected Peer-Reviewed Scholarly Publications
Funded Grants
Project: Molecular Toxicology of Bisphenol A
Role: PI
Agency: TSU Seed Grant
Duration: 12/1/2010-1/11/2012
Direct Support: $10,000
Project: Graduate Student Education and Development
Role: Co-PI
Agency: NIH/RCMI
Duration: 09/04-08/10
Direct Support Level: $733,000
Grant Number: RR03045-12A1
Project: Identification of Major Space Genes
Role: Co-PI
Agency: NASA/URC-TSU
Duration: 06/03-04/09
Direct Support: $670,000
Grant Number: NCC9-165 Project: Cellular and Molecular Toxicological
Evaluation of Bio-Nano Materials
Agency: NASA Texas Institute for Intelligent Bio-Nano Materials and
Structures for Aerospace Vehicles (TiiMS)
Role: Co-PI
Duration: 09/02-08/07
Direct Support: $50,000
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Project: Molecular Toxicology of Bisphenol A
Role: PI
Agency: Welch Foundation
Submitted: February 2013
Direct Support: $180,000
Project: miRNA Analysis of Bisphenol A Effect
Role: PI
Agency: Exiqon, Inc
Submitted: February 2011
Requested Support: $40,000
Project: Effect of Modeled Microgravity Environment on Expression Profiles
of microRNA in Human Lymphoblastoid Cells
Role: Co-PI
Agency: NASA (announcement NNH08ZTT003N)
Submitted: September 2008
Requested Support: $300,000
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