Bone loss and immune suppression in stressful physiological environments
Abstract:
Bone loss in microgravity is the second most important risk to space missions.
Exposure to the microgravity environment of space causes astronauts to lose calcium from bones. This loss occurs because the absence of Earth’s gravity disrupts the process of bone maintenance in its major function of supporting body weight.
Exposure to the microgravity environment of space causes men and women of all ages to lose up to 1% of their bone mass per month due to disuse atrophy, a condition like osteoporosis. It is not yet clear whether losses in bone mass will continue if a person remains in the microgravity environment or level off in time.
The mystery, for the moment, is what signals permit bone tissue to adapt to a weightless or an Earth (1 g) environment. Researchers do not yet know whether the biomechanical stimuli that are changed by microgravity directly affect osteoblast and osteoclast function or if other physiological factors such as hormone levels or poor nutrition contribute to bone loss. NASA investigators are studying gravity-sensing systems in individual bone cells by flying cultures of these cells on the Space Shuttle and observing how they function. Discoveries made during space biomedical research on bone are already contributing to a better understanding of osteoporosis and the treatment of bone mass loss on Earth as well as in space. The single most important contribution that NASA research has made to the understanding of bone deterioration in osteoporosis is heightened awareness of the importance of gravity, activity, and biomechanics – that is, the mechanical basis of biological activity – in bone remodeling.
Mechanical forces – the action of energy on matter – appear to coordinate bone shaping processes. The standard theory of bone remodeling states the body translates mechanical force into biochemical signals that drive the basic processes of bone formation and resorption. Aging, especially in post-menopausal women, and exposure to microgravity uncouple bone resorption and formation. When this uncoupling occurs, formation lags behind resorption, and the result is bone loss.Researchers are not yet certain whether bone resorption speeds up or the bone formation slows down, though recent experimentation in space indicates that microgravity might somehow affect both processes. Progress in developing methods of preventing or treating disuse atrophy and osteoporosis depends on better understanding the mechanisms that cause the problem. Determining how the body translates mechanical loading (physical stress or force) into the signals that control bone structure may reveal how aging, inactivity, and space flight uncouple bone formation and resorption. Only in the absence of gravity can we determine the influence of weight and stress on bone dynamics. By studying what mechanisms translates mechanical stress on bones into biochemical signals that stimulate bone formation and resorption, space life scientists may be able to determine how to maintain bone mass
Alamelu Sundaresan presently serves as the Chairperson- (Int) for the Department of Biology, housed in the College of Science, Engineering and Technology at Texas Southern University, Houston, Texas. The main goal of her research is to study human immunology in adverse environments, and what happens when the immune system is compromised such as in cancer, ageing, microgravity, nutritional deficiency, and auto immune conditions. We also work with nutritional supplements to improve the immune system towards global health solutions and collaborate internationally on this.
Main foci include bone tissue engineering (three patents), nutritional immunomodulation, mathematical modelling & toxicology of radiation, biophysics, particulates, and neurodegeneration. Dr Sundaresan is an Adjunct Faculty in the Dept of Surgery at UT health involved with inflammation, toxicity, and immune response. She is also a Visiting Scientist at NASA’s Johnson Space Centre in Houston.
She has authored more than 100 peer reviewed publications and 150 presentations. All her projects involve international collaboration. We work and network with many key collaborators in Denmark, Norway, Brazil, UK, and Germany to name a few. The lab is presently funded by the NSF, NIH, NASA, and industry.
Research Seminar
September 13, 2023
Location: SB 156
Time: 12:00 pm
Presenter: Dr. Ejiro Umaka
Probing the quark-gluon plasma with the sPHENIX detector
Abstract: sPHENIX is a new RHIC detector designed for high precision measurement of jets and heavy flavor probes of the quark-gluon plasma (QGP). sPHENIX is equipped with a suite of tracking detectors for vertexing, timing, and momentum measurement; calorimeters for photon, electron, hadron and jet measurements; and event characterization detectors for centrality and event plane measurements. sPHENIX’s first data began in late May 2023 primarily to commission the detector. Several physics observables including and not limited to jet correlations, jet substructure, open heavy flavor and upsilons are planned measurements with this year’s data and with data in the upcoming run in 2024. This talk will discuss probes of the QGP and sPHENIX readiness for these measurements.
Ejiro Umaka did her PhD work on ALICE at the LHC at CERN, which was granted to her in 2020 by the University of the Houston. She studied the QCD crossover temperature via net-particle fluctuation measurements in Pb-Pb collisions. She joined the sPHENIX collaboration at RHIC and the ATLAS collaboration at the LHC in 2020 studying jets and event plane dependent observables while she was a postdoctoral associate at Iowa State University. In 2022, she joined Brookhaven National Laboratory as a postdoctoral researcher where she continues to work on jet and flow related observables in sPHENIX. She is currently serving as sPHENIX juniors’ committee co-chair, software coordinator for sPHENIX event plane detector; and she is an avid yoga practitioner.
Light lunch will be provided.
Research Seminar
May 3, 2023
Location: SB 158
Time: 12:00 pm
Presenter: Dr. Nancy L. Glenn Griesinger
Harnessing Artificial Intelligence for Cancer Prognosis and Prediction: The Statistician’s Crucial Role – A Comprehensive Sequel
Abstract: Building upon last month’s award-winning presentation, this one-hour sequel delves into the resurgence of artificial intelligence (AI) and its application in machine learning for cancer prognosis and prediction. The discussion will include the relevance of computational biology and the incidence of intestinal polyps in ApcMin/+ mice, highlighting the connection between intestinal polyps and colon cancer from a clinical perspective. This joint presentation’s main focus will be the integral role of statisticians in developing predictive models using machine learning, as well as the benefits of utilizing nonparametric empirical likelihood theory based statistical models. We can achieve more accurate predictions by employing empirical likelihood and reducing dependence on distributional assumptions.
Nancy L. Glenn Griesinger is a tenured professor of mathematics and statistics with a Ph.D. in statistics from Rice University, who has been teaching at the university level for 21 years at universities in Texas, South Carolina, and California. Dr. Griesinger is also the founder and CEO of Mobile Math, LLC, a mathematics tutoring agency.
Light lunch will be provided.
Research Seminar
April 26, 2023
Location: SB 156
Time: 12:00 pm
Presenter: Dr. Jason Rosenzweig
“Bacterial Stress Responses”
Abstract: Prokaryotic bacteria are the oldest and most highly evolved beings on our planet. Due to their relatively small size, they have had to develop numerous mechanisms to survive in a much larger and often times hostile world. Bacteria are often faced with threatening biotic and abiotic stressors that they must either mitigate and/or survive. This seminar will focus on Gram-negative bacteria, and how they navigate host-cell induced stress, temperature stress, and chemical stress. More specifically, ribonucleases, enzymes involved in the maturation and degradation of RNA, and the multiprotein complex, the degradome, will be evaluated for their roles played during bacterial stress responses.
Light lunch will be provided
MCAT Prep Program
For more information please contact Dr. Ayodotun Sodipe Ayodotun.Sodipe@tsu.edu
Texas Southern University Summer Scholars Academy 2022
TSU Summer Scholar Academy participants with President, Dr. Lesia Crumpton-Young.
Texas Southern University hosted the Summer Scholars Academy, July 1 – August 1, 2022 housed in the Department of Biology, College of Science, Engineering and Technology (COSET). The academy was devoted to changing the lives of future leaders of tomorrow. Scholars were exposed to a dynamic curriculum in mathematics, science, coding, and forensics to expand their daily horizons. As an outreach program richly rooted in the heart of Third-Ward, Houston, Texas, educators and students spent their summer learning and creating tools to help them be more successful for the upcoming school year. Our goal at TSU is to provide an experience for students to be a part of the higher education spectrum with professors and community leaders to guide them. Our one-month program each year reaches over 150 students. This free community-based program works with surrounding organizations such as Houston Food Bank, HISD and Fort Bend ISD to provide high quality enrichment through instruction and nutrition.
TSU Summer Scholars Academy under the leadership of Dr. Ayodotun Sodipe, offered teachers accurate, unbiased, and up-to-date information on the role that science plays in our lives. The curriculum included essential principles and fundamental concepts of math and science. Instructors used an interactive framework that let students explore how science and math are used daily.
Front row: Summer Scholar participants; back row: Dr. Aladdin Sleem, Interim Dean, COSET, Dr. Ayodotun Sodipe, TSU Lead Professor and Ms. Charlotte Whaley, College Business Administrator.
Every week the University offered opportunities for all scholars to experience hands-on science learning with field trips. Students enjoyed a combination of science displays, group activities, and hands-on experiments. Activities were matched to the Texas Essential Skills also known as the TEKS. With certified educators and handpicked interns, students’ safety and knowledge were the key to success. With the help of President Crumpton-Young, our program was able to continue to support our students’ ambitions of being doctors, scientist, engineers, and teachers. TSU Summer Scholars program is committed to be the most respected STEM outreach program within the historic third-ward area. We are devoted to change, and foundational building that will lead our students to pursue a college on our campus.
Molecular Biology Research Lab
Supervisor: Desire Jackson SB 306
Dr. Jackson’s research focus is on the effects of heavy metal exposure on fetuses. The hypothesis behind this interest is: prenatal exposure to arsenic alters gene expression during development . In the laboratory, graduate students have examined the effect of arsenic at low levels on gene expression in rat pups during gestation and within two weeks of birth to determine the effects of gene expression. This work is important because the effects of arsenic exposure on gene expression in these developmental stages have not been well studied. The thought behind these studies is that prenatal exposure to Arsenic alters gene expression during development which may eventually lead to various tumor types in the adult organism. The prediction is that an alteration in gene expression will be seen when a comparison is made between the control and the arsenic -treated groups. Alteration of expression of genes associated with cell proliferation and DNA damage could be in the study group and could be linked to the potential for tumor formations in the adult.
Graduate students in her lab have used RNA isolation, RT-PCR and Quantitative Real Time PCR to study the effects of Arsenic exposure on the expression of specific genes associated with cell cycle regulation and oxidative stress. Students have studied the effects of pre- and peri-natal exposure to Arsenic on gene expression in fetal rat liver, in fetal rat kidney, and in fetal rat lung. Her students have also studies the effects of pre-natal exposure to Arsenic on gene expression in fetal rat kidney and in fetal rat brain.
Autophagy Lab
Supervisor: Mario Hollomon SB 304
Dr. Mario Hollomon’s laboratory investigates the effect of autophagy on cancer development and metastasis. Specifically, the laboratory investigates the effect of autophagy modulation on the sensitivity of cancer cells to anticancer therapy. Using lenitvirus, we have generated several stable knockdown cancer cell lines that have enabled the laboratory to investigate the effect of autophagy proteins on the response of cancer cells to anticancer drug treatment. We have shown that autophagy inhibition, through knockdown of ATG5, can have an opposing effect on osteosarcoma cells treated with camptothecin. We are currently investigating the mechanisms responsible for this opposing effect. We are also investigating the effect of other autophagy-related proteins on the response of cancer cells to anticancer drug treatment.
The laboratory also investigates cell death signaling pathways in cancer cells. Here, we also use lentivirus to knockdown the expression of select cell death pathway-associated proteins to better understand their role in the cell death pathway. In addition, the laboratory also investigates the role of endogenous antioxidants in protecting cancer cells against anticancer drug-induced cytotoxicity.
TSU-MAPS at AMEC in San Francisco
COSET students attended a banquet at the Annual Medical Education Conference where medical students were congratulated to their matching to a residency program.
Student National Medical Association (SNMA) was founded in 1964 as a sub-division of the (NMA) after recognizing the need to give active support to medical students and encourage them in their pursuit of careers as physicians. The Minority Association of Pre-Health Students (MAPS) represent the undergraduate and post-bac student-run chapters that extend the mission of SNMA and NMA: increasing the number of African-American, Latino, and other students of color entering and completing health professional schools. Texas Southern University chapter of SNMA-MAPS attended AMEC for the third time. SNMA 54thAnnual Medical Education Conference (AMEC) took place on March-28 to April 1, 2018 in San Francisco, California. Our MAPS chapter was able to take 20 students fully funded including travel, registration and hotel costs thanks to the support of Texas Southern University’s College of Science, Engineering, and Technology (COSET). This event allowed us to be exposed to diverse career opportunities, network with medical representatives, and build professional and academic skills. This event included many schools such as University of Chicago, Vanderbilt Medical School, Meharry Medical School, Howard Medical School, Harvard Medical School just to name a few.
Dr. A. Sodipe (Biology) and 20 students of the TSU-MAPS (Minority Association of Pre-Health Students) participated at the Annual Medical Education Conference
Contributed by: Dr. A. Sodipe and K.Kalifa
Dr. Marian Hillar invited to Oxford University
Biology professor Dr. Marian Hillar has been invited to present a seminar at the Ian Ramsey Centre for Science and Religion at Oxford University in England. The conference, to be held July 19-22, was organized in collaboration with the International Society for Science and Religion. The conference theme is Religion, Society, and the Science of Life. Dr. Hillar’s seminar, Natural Moral Law: From the Stoics to Kant, Darwin and Modern Evolutionary Science will detail that modern science provides a biological basis for human moral behavior and validates philosophical speculation. The presentation is based on his book, Historical Development toward Non-Theistic, Humanist Ethics: Essays from the Ancient Stoics to Modern Science.
Source: TSU E-newsJune 19-25,2017
TSU has been awarded a NSF Targeted Infusion Grant
From Left to right: Dr.Saydam (CO-I), Dr.Sapp (CO-I), Dr.Sundaresan (PI), Dr.Harvey (CO-PI), Dr.Peltier-Glaze (CO-I)
TSU was recently awarded a National Science Foundation Targeted Infusion Grant under PI, Dr. Alamelu Sundaresan, with Co-PI Dr. Mark Harvey and CO-Is Drs. John Sapp, Azime Saydam and Bernnell Peltier-Glaze. This project combines structured peer-mentor infused curricula coupled with faculty mentored summer research for the following courses within COSET: MATH 136, CHEM 131, PHYS 237 and BIOL 131. The main objective of the proposal is to increase STEM retention of underrepresented students by offering dedicated peer mentoring and supervised faculty research opportunities. We are excited about this first full-fledged project of its kind at TSU consisting of an active learning concept and associated peer-mentoring, which will benefit both TSU students and the above four departments from June 2017 – May 2020. Peer mentors will be selected from upperclassmen in each of the departments and will be directly supervised by the PI, Co-PI and CO-Is. More to follow…
Center for Philosophy, Religious, and Socinian Studies
The Center for Philosophy, Religious, and Socinian Studies conducts research and outreach on behalf of the largely unrecognized Socinian movement, its forefather Michael Servetus, and their profound influence on the development of the Enlightenment and beyond, including the foundation of American government. Over time, the Center has grown to encompass more than the Socinian movement to address relevant subjects in the fields of philosophy, ethics, humanism, and religion. The Center has produced dozens of publications (articles and books) and serves as an internationally recognized authoritative resource in these areas. The major work of Michael Servetus, forefather of freedom of religion, and freedom of conscience, was translated for the first time in the Center from original Latin into English (five volumes).
Director
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Contact Information
Prof. Marian Hillar, M.D., Ph.D.
Professor of Philosophy and Religious Studies
Department of Biology
Texas Southern University
Projects
Current project involves preparation of a monograph on the development of the Socinian movement in Europe and the United States and its effect of the formation of the American Constitution.
Evaluation of commonalities in major world religions in order to build a consensus in public morals in a pluralistic society.
Investigators
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Mrs. Clare Allen (Stettler), M.A.
Research Assistant
Research and Services
The Center conducts historical research in the areas of history of ideas, philosophy, and religions and attempts to build a consensus to provide an intellectual guidance to modern times. Research and publications of the Center are internationally recognized as being in the forefront of the scholarly efforts in the subject.
Recently the Center developed a new course offered at the Department of Biology entitled : History and Philosophy of Science, BIO 435
Labs and Equipment
The Center requires access to library sources and use of modern and classical languages. Modern Internet is an invaluable tool for access to such resources, as well as access to Fondren Library in Houston. Also several library resources in foreign countries at major universities were utilized for research.
Short Introduction
Mausoleum of Faustus Socinus
Socinians were members of the specific radical Reformation international religious group that was formed originally in Poland and in Transylvania in the XVIth century and went beyond the limited scope of the reform initiated by Luther or Calvin. At the roots of their religious doctrines was the Antitrinitarianism developed by Michael Servetus (1511-1553) and transplanted by Italian Humanists, as well as the social ideas borrowed initially from the Anabaptists and Moravian Brethren. About the middle of the XVIth century a variety of Antitrinitarian sects emerged. They called themselves Christians or Brethren, hence Polish Brethren, also Minor Reformed Church. Their opponents labeled them after the old heresies as Sabellians, Samosatinians, Ebionites, Unitarians, and finally Arians. They were also known abroad as Socinians, after the Italian Faustus Socinus (1539-1604) (Fausto Sozzini, nephew of Lelio Sozzini) who at the end of the XVIth century became a prominent figure in the Raków Unitarian congregation for systematizing the doctrines of the Polish Brethren. Although the spirit of religious liberty was one of the elements of the Socinian doctrine, the persecution and coercion they met as a result of the Counter Reformation led them to formulate the most advanced ideas in the realm of human freedom and church-state relations.The intellectual ferment Socinian ideas produced in all of Europe determined the future philosophical trends and led directly to the development of Enlightenment. The precursor ideas of the Polish Brethren on religious freedom were later expanded, perfected and popularized by John Locke (1632-1704) in England , Pierre Bayle (1647-1706) in France and Holland, and Baruch Spinoza (1632-1677) in Holland. The ideas of John Locke were transplanted directly to the American continent by James Madison and Thomas Jefferson who implemented them for the first time in the American legislation.
Figure 1
The Polish Brethren were forerunners of the later thinkers who developed the ideas of the Enlightenment and introduced modern humanistic ideals. Their achievements are the highest in Europe of their times and originated all modern trends in political, social and moral sciences, in biblical and religious studies, and in concepts of the absolute freedom of intellectual inquiry, liberty of conscience and complete nonantagonistic separation of church and state. They put to practice the highest ethical ideals.The doctrines of the Polish Brethren represented a humanistic reaction to a medieval theology based on submission to the Church’s totalitarian authority. Though they retained the scripture as something supra rationem, they analyzed it rationally and believed that nothing should be accepted contra rationem. Their social and political thought underwent a significant evolutionary process from the very utopian trend condemning participation in war and holding public and judicial office to a moderate and realistic stand based on mutual love, support of the secular power of the state, active participation in social and political life, and defense of social equality. They spoke out against the enserfment of peasants, a recurring issue in Poland not solved until the XXth century.
Figure 2
They were the first to postulate the complete separation of church and state, an idea never before discussed in Christian societies. Their spirit of absolute religious freedom expressed in their practice and writings, “determined, more or less immediately, all the subsequent revolutions in favor of religious liberty.” Their rationality set the trend for the philosophical ideas of the Enlightenment and determined future development of all modern intellectual endeavors. After expulsion they were forced into oblivion for three centuries, forgotten in a country that continued to be dominated by the Catholic Church.
Raphael – School of Athens
Statue of Michael Servetus in Villanueva de Sijena
The intellectual ferment Socinian ideas produced in all of Europe determined the future philosophical trends and led directly to the development of Enlightenment. The precursor ideas of the Polish Brethren on religious freedom were later expanded, perfected and popularized by John Locke (1632-1704) in England and Pierre Bayle (1647-1706) in France and Holland. The ideas of John Locke were transplanted directly to the American continent by Thomas Payne, James Madison, Thomas Jefferson, and others and were implemented them for the first time in the American legislation.
The project of studies involves: 1. Translation of the original works written by Michael Servetus from Latin into English; 2. Recovery of writings of the Socinians and spreading the information about their ideas; 3. Tracing the development of ideas which eventually led to the formation of American society and its Constitution with all its ideals and freedoms.
Books written and edited, published during the last ten years
Marian Hillar, Robert D. Finch, editors “Essays in the Philosophy of Humanism,” Vol. 14, pp. 90. American Humanist Association, 2006.
Marian Hillar, Robert D. Finch, editors “Essays in the Philosophy of Humanism,” Vol. 15, pp. 160. American Humanist Association, 2007.
Marian Hillar, Robert D. Finch, editors “Essays in the Philosophy of Humanism,” Vol. 16 (1) Spring-Summer, pp. 96. American Humanist Association, Washington, DC, 2008.
Marian Hillar, Robert D. Finch, editors “Essays in the Philosophy of Humanism,” Vol. 16 (2) Fall-Winter, pp. 120. American Humanist Association, Washington, DC, 2008.
Marian Hillar, Robert D. Finch, editors “Essays in the Philosophy of Humanism,” Vol. 17 (1) Spring-Summer, pp. 112. American Humanist Association, Washington, DC, 2009.
Marian Hillar, and Christopher A. Hoffman, translators: “The Restoration of Christianity. An English Translation of Christianismi restitutio, 1553, by Michael Servetus (1511-1553). Translated by
Christopher A. Hoffman and Marian Hillar,” (Lewiston, NY; Queenston, Ont., Canada; Lampeter, Wales, UK: The Edwin Mellen Press, 2007). Pp. 409+xxix
Marian Hillar, and Christopher A. Hoffman, translators: “Treatise on Faith and Justice of Christ’s Kingdom by Michael Servetus. Selected and Translated from Christianismi restitutio by Christopher A. Hoffman and Marian Hillar,” (Lewiston, NY; Queenston, Ont., Canada; Lampeter, Wales, UK: The Edwin Mellen Press, 2008). Pp. 95 +xlv
Marian Hillar, and Christopher A. Hoffman, translators: “Treatise Concerning the Supernatural Regeneration and the Kingdom of the Antichrist by Michael Servetus. Selected and Translated from Christianismi restitutio by Christopher A. Hoffman and Marian Hillar,” (Lewiston, NY; Queenston, Ont., Canada; Lampeter, Wales, UK: The Edwin Mellen Press, 2008). Pp. 302+l
Marian Hillar, Robert D. Finch, editors “Essays in the Philosophy of Humanism,” Vol. 16 (2) Fall Winter, pp. 120. American Humanist Association, Washington, DC, 2008.
Marian Hillar, Robert D. Finch, editors “Essays in the Philosophy of Humanism,” Vol. 17 (1) Spring-Summer, pp. 114. American Humanist Association, Washington, DC, 2009.
Marian Hillar, Robert D. Finch, editors “Essays in the Philosophy of Humanism,” Vol. 17 (2) Fall-Winter, pp. 130. American Humanist Association, Washington, DC, 2009.
Marian Hillar, Robert D. Finch, editors “Essays in the Philosophy of Humanism,” Vol. 18 (1) Spring-Summer, pp. 96. American Humanist Association, Washington, DC, 2010.
Marian Hillar, Robert D. Finch, editors “Essays in the Philosophy of Humanism,” Vol. 18 (2) Fall-Winter pp. 108. American Humanist Association, Washington, DC, 2010.
Marian Hillar, and Christopher A. Hoffman, translators: “Thirty Letters to Calvin & Sixty Signs of the Antichrist by Michael Servetus.” Translated from Christianismi restitutio by Christopher A. Hoffman and Marian Hillar (Lewiston, NY; Queenston, Ont., Canada; Lampeter, Wales, UK: The Edwin Mellen Press, 2010). Pp. 175 + lxxxvi.
Juan Naya and Marian Hillar, eds., “Michael Servetus, Heartfelt: Proceedings of the International Servetus Congress, Barcelona, 20-21 October, 2006,” (Lanham, MD and Plymouth UK: University Press of America, 2011). 430 pp.
Marian Hillar, Robert D. Finch, editors “Essays in the Philosophy of Humanism,” Vol. 19 (1) Spring-Summer, pp. 106. American Humanist Association, Washington, DC, 2011.
Marian Hillar, Robert D. Finch, editors “Essays in the Philosophy of Humanism,” Vol. 19 (2) Fall-Winter, pp. 116. American Humanist Association, Washington, DC, 2011.
Marian Hillar, founding editor, “Essays in the Philosophy of Humanism,” Vol. 20 (1) Spring-Summer, pp. 106. American Humanist Association, Washington, DC, 2012.
Marian Hillar, founding editor “Essays in the Philosophy of Humanism,” Vol. 20 (2) Fall-Winter pp. 126. American Humanist Association, Washington, DC, 2012.
Marian Hillar, Major study: From Logos to Trinity. The Evolution of Religious Beliefs from Pythagoras to Tertullian (Cambridge, UK, New York: Cambridge University Press, 2012), 320 pp. + xi.
Marian Hillar, founding editor, “Essays in the Philosophy of Humanism,” Vol. 21 (1) Spring-Summer, pp. 120. American Humanist Association, Washington, DC; Equinox Sheffield, UK, 2013.
Marian Hillar, founding editor “Essays in the Philosophy of Humanism,” Vol. 21 (2) Fall-Winter pp. 126. American Humanist Association, Washington DC; Equinox, Sheffield, UK, 2013.
Marian Hillar, founding editor “Essays in the Philosophy of Humanism,” Vol. 22 (1) pp. 118. American Humanist Association, Washington, DC; Equinox, Sheffield, UK, 2014.
Marian Hillar, founding editor “Essays in the Philosophy of Humanism,” Vol. 22 (2) pp. 120. American Humanist Association, Washington, DC; Equinox, Sheffield, UK, 2014.
Marian Hillar, founding editor “Essays in the Philosophy of Humanism,” Vol. 23 (1) pp. 132. American Humanist Association, Washington, DC; Equinox, Sheffield, UK, 2015.
Marian Hillar, founding editor “Essays in the Philosophy of Humanism,” Vol. 23 (2) pp. 128. American Humanist Association, Washington, DC; Equinox, Sheffield, UK, 2015.
Marian Hillar, and Christopher A. Hoffman, translators: “Regarding the Mystery of the Trinity and the Teaching of the Ancients to Philip Melanchthon and His Colleagues”
by Michael Servetus. Translated from Christianismi restitutio by Marian Hillar and Christopher A. Hoffman (Lewiston, NY; Queenston, Ont., Canada; Lampeter, Wales, UK: The Edwin Mellen Press, 2015), 103 pp + lii.
Marian Hillar, “The Historical Development Toward a Non-Theistic Humanistic Ethics: Essays from the Ancient Stoics to Modern Science.” (Lewiston, NY; Queenston, Ont., Canada; Lampeter, Wales, UK: The Edwin Mellen Press, 2015), 278 pp + lxii.
Journal publications in the last ten years
Marian Hillar,.”Socinian Precursors of the American Constitutional Separation of Church and State. Part II : Socinian Ideas on the Separation of State and Religion.” In The American Unitarian, Vol. 5, No. 2, June 2006, pp. 60-74.
Marian Hillar and Claire S. Stelter, translation from Polish of an article by Stanisław Cieniawa, “Let’s Learn Religion from … Flowers.” Published in Essays in thePhilosophy of Humanism, American humanist Association, Washington, D.C., Vol. 14, 2006, pp. 69-77.
Marian Hillar, “Christianismi restitutio (Restitución del Cristianismo): el programa religioso de Miguel Servet,” in Miguel Servet. Luz entre tinieblas, ed. Sergio Baches Opi, (Huesca: Instituto de Estudios Sijenenses, 2006), pp. 45-68.
Marian Hillar, “Christianismi restitutio (Restoration of Christianity): the religious program of Michael Servetus,” in Miguel Servet. Luz entre tinieblas, (Huesca: Instituto de Estudios Sijenenses, 2006), pp. 69-92.
Marian Hillar, “El legado de Servet. El camino del reconocimiento de la libertad de conciencia como derecho natural y cambio de paradigma social: de Servet a Thomas Jefferson,” in Miguel Servet. Luz entre tinieblas, ed. Sergio Baches Opi, (Huesca: Instituto de Estudios Sijenenses, 2006), pp. 93-108.
Marian Hillar, “The legacy of Servetus: Humanism and the beginning of change in the social paradigm: From Servetus to Thomas Jefferson, in Miguel Servet. Luz entre tinieblas, ed. Sergio Baches Opi, (Huesca: Instituto de Estudios Sijenenses, 2006), pp. 109-124.
Marian Hillar, “Numenius and Greek Philosophical Sources of Christian Doctrine.” In Proceedings of the Twenty-First World Congress of Philosophy, Istanbul. August 10- 17, 2003, (Turkish Philosophical Society, Ankara, 2006), Vol. 8, pp. 55-60.
Marian Hillar, “The Religious program of Michael Servetus in His major Work, Christianismi restitutio (The Rstoration of Christianity).” Journal from the Radical Reformation. Testimony to Biblical Unitarianism, Vol. 13, No. 2. Fall, 2006. pp. 2-19.
Marian Hillar, “Servetus and the Switch to the Humanistic Social Paradigm. An Historical Perspective on How the Social Paradigm Changes.” In Essays in the Philosophy of Humanism, eds. Robert D. Finch, Marian Hillar, American Humanist Association, Houston, Vol. 15, 2007, pp. 91-116.
Marian Hillar, “Friedrich Nietzsche: The Genealogy of Morals. The First Essay. ‘Good and Evil,’ ‘Good and Bad’ and the Critique of the Christian Ethics.” In Houston Freethought Alliance Newsletter, Issue 92, July 2007, pp. 3-7.
Marian Hillar, “Numenius and the Hellenistic Sources of the Central Christian Doctrine” in A Journal from the Radical Reformation. A testimony to Biblical Unitarianism. Vol. 14, No. 1, Spring 2007, pp. 3-31.
Marian Hillar, “Friedrich Nietzsche: The Genealogy of Morals. The Second Essay. ‘Guilt,’ ‘Bad Conscience,’ and Related Matters.” In Houston Freethought Alliance Newsletter, Issue 94, August 2007, pp. 3-5.
Marian Hillar, “Friedrich Nietzsche: The Genealogy of Morals. The Third Essay: ‘What Do Ascetic Ideals Mean?’ (1) The Ascetic Ideal in Art. (2) The Philosopher’s Ascetic Ideal.” In Houston Freethought Alliance Newsletter, Issue 95, September 2007, pp. 5-7.
Marian Hillar, “Friedrich Nietzsche: The Genealogy of Morals. The Third Essay: “What Do Ascetic Ideals Mean?” (3) The Priest and His Ascetic Ideal (4) The Human Condition and the Function of Ascetic Priests. In Houston Forethought Alliance Newsletter, Issue 96, October 2007, p. 5.
Marian Hillar, “Friedrich Nietzsche: The Genealogy of Morals. The Third Essay: “What Do Ascetic Ideals Mean?” (5) Mechanisms of Alleviating Depression and Corruption of Mental health (6) What Does the Ascetic Ideal Signify? Its Implications for Atheism. In Houston Freethought Alliance Newsletter, Issue 97, November 2007, pp. 4-6.
Marian Hillar, “Process Theology and Process thought in the Writings of Michael Servetus” in A Journal from the Radical Reformation. A testimony to Biblical Unitarianism. Vol. 14, No. 2, Fall 2007, pp. 31-38.
Marian Hillar, book review of “Socinianism and Arminianism. Antitrinitarians, Calvinists and Cultural Exchange in Seventeenth-Century Europe” Martin Mulsow and Jan Rohls, eds. (Leiden, Boston: Brill, 2005, ix + 306 pp.). In Houston Forethought Alliance Newsletter, Issue 98, December, 2008, pp. 6-7.
Marian Hillar, “Moral Philosophy and Modern Science. Modern Science provides a Biological basis for Human Behavior and Validates Philosophical Speculation.” In Houston Freethought Alliance Newsletter, Issue 99, January, 2008, pp. 5-6.
Marian Hillar, “Humanist Ethics. A Global Ethics.” In Houston Freethought Alliance Newsletter, Issue 100, February 2008, pp. 5-6.
Marian Hillar, “The Stoic Ethics: Natural Development, Rationality, and Responsibility.” (1) Myth and Philosophy. In Houston Freethought Alliance Newsletter, Issue 101, February 2008, pp. 5-6.
Marian Hillar, “Friedrich Nietzsche: Social Origin of Morals, Christian Ethics, and Implications for Atheism in His The Genealogy of Morals,” published in the Essays in the Philosophy of Humanism, Vol. 16 (1), 2008, pp. 71-96.
Marian Hillar, “The Stoic Ethics: Natural Development, Rationality, and Responsibility. (2) Fundamentals of Stoic Ethics.” In Houston Freethought Alliance Newsletter, Issue 102, March, 2008, pp. 5-6.
Marian Hillar, “The Stoic Ethics: Natural Development, Rationality, and Responsibility. (3) Development of the Concept of Values.” Published in the Houston Freethought Alliance Newsletter, issue 103, May 2008, pp. 6-8.
Marian Hillar, “The Stoic Ethics: Natural Development, Rationality, and Responsibility. (4) Development of Virtue, the Paradigm of the Sage, and Philosophical determinism.” Published in the Houston Freethought Alliance Newsletter, issue 104, June 2008, pp. 5-7.
Marian Hillar, “The Stoic Ethics: Natural Development, Rationality, and Responsibility. (5) Moral Responsibility.” Published in the Houston Freethought Alliance Newsletter, issue 105, July, 2008, pp. 6-9.
Marian Hillar, “The Stoic Ethics: Natural Development, Rationality, and Responsibility. (6) Rational Assent. Impact of the Stoic Ethical Theory. Similarity with the Indian Thought. Confirmation by Modern Science.” Published in the Houston Freethought Alliance Newsletter, issue 106, August, 2008, pp. 3-5.
Marian Hillar, “Roots of Humanist Ethics: A Historical perspective. Kant’s Moral Philosophy and its Reinterpretation. A Quintessential Humanistic Doctrine” (1). Published in the Houston Freethought Alliance Newsletter, issue 107, September, 2008, pp. 3-4.
Marian Hillar, “Roots of Humanist Ethics: A Historical perspective. Kant’s Moral Philosophy and its Reinterpretation. A Quintessential Humanistic Doctrine” (2). Published in the Houston Freethought Alliance Newsletter, issue 108, October, 2008, pp. 3-5.
Marian Hillar, “Roots of Humanist Ethics: A Historical perspective. Kant’s Moral Philosophy and its Reinterpretation. A Quintessential Humanistic Doctrine” (3). Published in the Houston Freethought Alliance Newsletter, issue 109, November, 2008, pp. 3-5.
Marian Hillar, “Roots of Humanist Ethics: A Historical perspective. Kant’s Moral Philosophy and its Reinterpretation. A Quintessential Humanistic Doctrine” (4). Published in the Houston Freethought Alliance Newsletter, issue 110, December, 2008, pp. 3-5.
Marian Hillar, Roots of Humanist Ethics: A Historical Perspective. Jürgen Habermas: A Practical Sense Sociologist and a Kantian Moralist in a Nutshell (1). Published in the Houston Freethought Alliance Newsletter, issue 111, January 2009, pp. 3-4.
Marian Hillar, Roots of Humanist Ethics: A Historical Perspective. Jürgen Habermas: A Practical Sense Sociologist and a Kantian Moralist in a Nutshell (2). Published in the Houston Freethought Alliance Newsletter, issue 112, February 2009, pp. 3-4.
Marian Hillar, Roots of Humanist Ethics: A Historical Perspective. Jürgen Habermas: A Practical Sense Sociologist and a Kantian Moralist in a Nutshell (3). Published in the Houston Freethought Alliance Newsletter, issue 113, March 2009, pp. 3-4.
Marian Hillar, Roots of Humanist Ethics: A Historical Perspective. Jürgen Habermas: A Practical Sense Sociologist and a Kantian Moralist in a Nutshell (4). Published in the Houston Freethought Alliance Newsletter, issue 114, April 2009, pp. 3-4.
Marian Hillar, Roots of Humanist Ethics: A Historical Perspective. Jürgen Habermas: A Practical Sense Sociologist and a Kantian Moralist in a Nutshell (5). Published in the Houston Freethought Alliance Newsletter, issue 115, May 2009, pp. 3-4.
Marian Hillar, Roots of Humanist Ethics: A Historical Perspective. Jürgen Habermas: A Practical Sense Sociologist and a Kantian Moralist in a Nutshell (6). Published in the Houston Freethought Alliance Newsletter, issue 116, June 2009, pp. 3-5.
Marian Hillar, Roots of Humanist Ethics: A Historical Perspective. Jürgen Habermas: A Practical Sense Sociologist and a Kantian Moralist in a Nutshell (7). Published in theHouston Freethought Alliance Newsletter, issue 117, July 2009, pp. 3-4.
Marian Hillar, Foundation of Kant’s Moral Philosophy and its Reinterpretation: A Quintessentail Humanisstic Doctrine, published in the Essays in the Philosophy of Humanism, Vol. 17 (1), Spring-Summer 2009, pp. 71-90.
Marian Hillar, Roots of Humanist Ethics: A Historical Perspective. Benedict Spinoza and His Revival of Naturalistic Ethics (1). Published in Houston Freethought Alliance Newsletter, issue 119, October 2009, pp. 3-4.
Marian Hillar, “Discovery of a New Species of Human Ancestors: Ardipithicus Ramidus,” Published in Houston Freethought Alliance Newsletter, issue 120, November 2009, pp. 4-5.
Marian Hillar, “Roots of Humanist Ethics: A Historical Perspective. Benedict Spinoza and His Revival of Naturalistic Ethics “(2). Published in Houston Freethought Alliance Newsletter, issue 121, November 2009, pp. 4-5
Marian Hillar, “The Polish Socinians: Contribution to Freedom of Conscience and the American Constitution,” in Dialogue and Universalism, Vol. XIX, No. 3-5, 2009.
Marian Hillar, “Roots of Humanist Ethics: A Historical Perspective. Benedict Spinoza and His Revival of Naturalistic Ethics” (3). Published in Houston Freethought Alliance Newsletter, issue 122, January 2010, pp. 6-7.
Marian Hillar, “What Does Modern Science Say about the Origin of Religion?” Published in the Houston Freethought Alliance Newsletter, issue 123, February 2010, pp. 4-8
Marian Hillar, “Roots of Humanist Ethics: A Historical Perspective. Benedict Spinoza and His Revival of Naturalistic Ethics” (4). Published in Houston Freethought Alliance Newsletter, issue 125, April 2010, pp. 6-7.
Marian Hillar, book review of Rodrigue Tremblay, The Code for Global Ethics. Ten Humanist Principles. Preface by Paul Kurtz (Amherst, NY: Prometheus Books, 2010). Published in Houston Freethought Alliance Newsletter, issue 126, May 2010, pp. 10-12.
Marian Hillar, “What Does Modern Science Say about the Origin of Cooperation? Science Confirms Philosophy.” Published in Houston Freethought Alliance Newsletter, issue 127, June 2010, pp. 3-7.
Marian Hillar, “What Does Modern Science Say about the Origin of Cooperation? Science Confirms Philosophy.” Published in the Essays in the Philosophy of Humanism, Vol. 18 (2), Fall – Winter 2010, pp. 43-52.
Marian Hillar, “Why the Memory of Servetus Should be Kept Alive: A Historical Perspective,” a chapter in the book: Juan Naya and Marian Hillar, eds., “MichaelServetus, Heartfelt: Proceedings of the International Servetus Congress, Barcelona, 20-21 October, 2006,” (Lanham, MD and Plymouth UK: University Press of America, 2011). pp. 267-298.
Marian Hillar, ”Jürgen Habermas: A Practical Sense Sociologist and a Kantian Moralist in a Nutshell.” Published in the Essays in the Philosophy of Humanism, Vol. 19 (2), Fall –Winter 2011, pp. 1-26.
Marian Hillar, “Lelio et Faust Socin: fondateurs du socinianisme, leurs vies et théologie,” traduit en français par Christian Callas. Published in Cahiers Michel Servet, No. 16, février 2012, pp. 1-26.
Marian Hillar, “Dziedzictwo Braci Polskich. Rozdział Religii od Państwa i Wolność Sumnienia.” (“The Legacy of the Polish Brethren. Separation of Religion and State and Freedom of Conscience.”) Published in Gazeta AMG, a monthly of the Medical University of Gdańsk, Vol. 22, July, 2012, No. 7 (259), pp. 34-38.
Marian Hillar, “Philo’s Logos Doctrine. Bridging the two Cultures and Creating the Philosophical and Theological Foundations of Christianity,” in Dialogue and Universalism Vol. XXI, (4) 2012, pp. 59-90.
Marian Hillar, “What Does Modern Science Say about the Origin of Religion?” in in Dialogue and Universalism Vol. Vol. XXII (4) 2012, pp. 111-120.
Marian Hillar, “Creationism and Evolution. Misconceptions about Religion and Science.” in Dialogue and Universalism Vol. XXII (4) 2012, pp. 133-160.
Marian Hillar, “Servet y el nuevo paradigma histórico” Chapter in a book :“Miguel Servet. Los valores de un hereje,” Heraldo de Aragón, 2013, pp. 100-102.
Marian Hillar, “What Does Modern Science Say about the Origin of Cooperation? Science Confirms Philosophy” in Dialogue and Universalism, Vol. XXIII (3) 2013, pp. 23-34.
Marian Hillar, “Dziedzictwo Serveta” (“Legacy of Servetus”), published in Pistis, wrzesień (September) 2011, pp. 27-31. This is a translation (by Rafał Sajna) into Polish of “The Legacy of Servetus: Humanism and the Beginning of Change in the Social Paradigm. On the Occasion of the 450th Anniversary of His Martyrdom.” In A Journal from the Radical Reformation. A Testimony to Biblical Unitarianism. Vo. 11, No. 2, Winter 2003, pp. 34-41.
Marian Hillar, “Philo on Evil.” An article for the Encyclopedia of Evil. Scheduled for publication in June 2016.
Conference papers and presentations during the last ten years
“Hellenistic Sources of Post-Nicene Christianity.” Paper read at the 4th Annual Hawaii International Conference on Arts and Humanities, Honolulu, Hawaii, January 11 – 14, 2006.
“Jesus after 2000 Years – Question of Historicity of Jesus.” Seminar of the Ideas Club, Humanists of Houston, February 26, 2006.
“Freedom of Conscience and Michael Servetus: The beginning of change of the Social Paradigm.” Paper read at the meeting of the South-Central Renaissance Conference, St. Thomas University, Houston, TX, March 9-11, 2006.
“The Existence of God and Atheism.” Seminar for the Humanists of Houston, July 15, 2006.
“¿Porqué hay que mantener viva la memoria de Servet?” Seminar presented at the International Servetus Congress, Barcelona, Spain, October 20-21, 2006.
Review of the book by Richard Dawkins “The God Delusion,” Ideas Club. Houston, January 21, 2007.
Review of the book by Richard Dawkins “The God Delusion,” Science and Religion Discussion, Melanchthon Institute, Houston, Texas, February 16, 2007.
Seminar “The First Translation into English of the First Part of Christianismi restitutio of Michael Servetus and Evaluation of its Theology.” South-Central Renaissance Conference, San Antonio, Texas, March 8-10, 2007.
Paper read at the International Meeting of the Society of Biblical Literature, “The First Translation of the First Part of Christianismi restitutio of Michael Servetus and the Evaluation of its Biblical Theology.” Vienna, July 22-27, 2007, pp. 25-33.
Seminar for the Ideas Club, Humanists of Houston, “Does Modern Science Invalidate Philosophy? Modern Science and Ethics.” Ideas Club of Humanists of Houston, September 23, 2007.
Seminar for Religion, Ethics, and Society Club, “Psychology of Atheism According to Nietzsche’s Third Essay in Genealogy of Morals,” Houston, November 24, 2007.
Seminar for Science and Religion Discussion Group, “Habermas on Society and Religion,” Christ the King Lutheran Church, Houston, TX January 18, 2008.
Seminar presented for Science and Religion Discussion Group, “Modern Science and Ethics. Part I, Philosophical Ethical Inquiry,” Christ the King Lutheran Church, Houston, TX November 14, 2008.
Paper “Natural Moral Law and the Modern Evolutionary Science. Reinterpretation of the Natural Law and Moral PHILOSOPHY.” Presented at the 7th Annual Hawaii International Conference on Arts and Humanities, Honolulu, Hawaii, January 9 – 12, 2009.
Seminar presented at the Texas Academy of Sciences meeting, “Radiation and Radiation Safety,” Texas Tech University, Junction, TX, March 5-7, 2009
Seminar for Research Week, Texas Southern University, “What Does Modern Science Say about the Origin of Human Morality?” Houston, TX April 3, 2009.
Seminar presented for Science and Religion Discussion Group: “How a Religious Belief Led to the Discovery of the Pulmonary Blood Circulation.” Christ the King Lutheran Church, Houston, April 17, 2009.
Seminar presented for the Humanists of Houston: “Michael Servetus (1511-1553): Theologian, Philosopher, Scientist, and Humanist.” Houston, May 15, 2009.
Seminar presented for the Science and Religion Discussion Group: “Conflict between Science and Religion.” Christ the King Lutheran Church, Houston, October 16, 2009.
Seminar for Ideas Club, “The Last professors,” review of the book by Donoghug “The last professors.” Houston, October 24, 2009
Seminar for Religion, Ethics and Society Club, “Review of the Book by Sanford Rives, ‘Did Calvin Murder Servetus?,’” Houston, November 28, 2009.
Seminar for the Essays in the Philosophy of Humanism Symposium, “Moral Philosophy and Religion Facing Science. Humanistic Synthesis.” Presented at 69th Annual Conference of the American Humanist Association, San Jose CA, June 4-6, 2010.
Conference with the Editors and Contributors to Dialogue and Universalism, an international philosophical Journal published in Warsaw, “Polish Brethren (Socinians) and Their Role in the European History,” Warsaw July 22, 2010.
Lecture: “Michael Servetus: Intellectual Giant, Humanist, and Martyr,” lecture for the Thoreau Woods Unitarian Universalist Church, Huntsville, TX, September 19, 2010.
Seminar for Science and Religion Discussion Group: “What Does Modern Science Say about the Origin of Cooperation?” Christ the King Lutheran Church, Houston Texas, October 15, 2010.
Seminar for TSU Interdisciplinary Research Conference: “Regulation and Control in Biological Systems and Beyond …” Texas Southern University, November 4, 2010.
Paper “Natural Foundation of Moral Philosophy,” Presented at the 9th Annual Hawaii International Conference on Arts and Humanities, Honolulu, Hawaii, January 9 – 12, 2011.
Seminar for Open House, Physics Department at Texas Southern University, “Biological Effects of Radiation,” Houston, March 30, 2011.
Seminar “Natural Moral law and Modern Evolutionary Science. Reinterpretation of the Natural Law,” presented for Essays in the Philosophy of Humanism Symposium, American Humanist Association, Cambridge, MA, April 7-10, 2011.
Seminar “What Unitarian Universalists Should Know about Socinians?” Presented for the Emerson Unitarian Church, Houston, June 26, 2011.
Seminar for the Ideas Club, Humanists of Houston, “From the Polish Brethren or Socinians to Liberal Religion or How the Modernity was Introduced into the Western World?” August, 28, 2011.
Seminar: “The Legacy of Michael Servetus: the Radical Change in the Thought Pattern, Freedom of Conscience and a Switch to the Humanistic Moral Social Paradigm.”
The Keynote speaker at the Conference “The Western Heritage of Humanism, Skepticisn, and Freethought. Toward a Reasonable World.” Organized by the Department of Religious Studies at the San Diego University and the Institute for the Study of American Religion. San Diego, September 16-18, 2011.
Seminar for Science, Religion Discussion Group, Christ the King Lutheran Church, “Evolution of the Messianic Expectations in the Hebrew Culture: Hebrew Bible, the Writings of the Dead Sea Scrolls, the Pseudoepigrapha,” Houston, November 18, 2011.
Seminar for Radiation Safety Training Workshop, “Biological Effects of Radiation,” Texas Southern University, Houston, November 18, 2011.
Seminar for the Science and Religion Discussion Group, Christ the King Lutheran Church, “Philo of Alexandria: Bridging the Hebrew Religion with the Greek Philosophy and Religion,” Houston, May 18, 2012.
Seminar for Polish Philosophical Society, Editorial Board of “Dialogue and Universalism,” and Institute of Philosophy and Social Sciences of the Polish Academy of Sciences, “Rozwój Hellenistyczno-Judeo-Chrześcijańskich Wierzeń Religijnych od Pitagorasa do Tertuliana,” (“Evolution of the Hellenistic, Judaic, and Christian religious Beliefs from Pythagoras to Tertullian”) Warsaw, May 29, 2012.
Seminar for the Editorial Board of “Dialogue and Universalism,” “Dziedzictwo Braci Polskich: Rozdział Religii od Państwa i Wolność Sumienia,” (“The Legacy of the Polish Brethren: Separation of Religion from State and Freedom of Conscience”) Warsaw, June 2, 2012.
Seminar for Religion, Ethics and Society Club, “Naturalistic Spirituality: Beauty of Our Earth and Wisdom of Sages Houston, August 25, 2012.
Seminar for Radiation Safety Training Workshop, “Biological Effects of Radiation,” Texas Southern University, Houston, October 26, 2012.
Seminar for Religion, Ethics and Society Club, “Does Archaeology Prove the Existence of Jesus? An Alternative Explanation.” Houston, October 27, 2012.
Seminar for College of Science and Technology, Texas Southern University, Houston: “Creationism and Evolution: Misconceptions about Science and Religion.” Houston, December 3, 2012.
Seminar for the Science and Religion Discussion Group, Christ the King Lutheran Church, /> “From the Polish Socinians to the American Constitution. A Study in Freedom of /> Conscience.” Houston, January 18, 2013.
Paper, “The Stoic logic and Egyptian divine metaphysics as the sources of the />Tertullian doctrine of the Trinity.” Presented at the XXIII World Congress of Philosophy, Athens, Greece, August 4-10, 2013.
Seminar for Science and religion Discussion Group, Christ the King Lutheran Church, Houston, September 20, 2013.
“Does Archaeology Prove the Existence of Jesus? An Alternative Explanation.” Houston, September 20, 2013.
Presentation : “Turkish Language School at the Fatih University, Istanbul,” for the Raindrop Turkish Center, Houston, August 19, 2013.
Presentation : “Reading Poetry for the World Poetry Day,” poems by Pablo Neruda, Charles Baudelaire, Haether Dolohau, and Orhan Veli Kanik. For the Raindrop Turkish Center, Houston, April 10, 2014.
Presentation : “Photosynthesis: Its Discovery and How Does it Work?” Presentation for the Science and Religion Discussion Group, Christ the King Lutheran Church, Houston, April, 21, 2014.
Seminar : “How to Think about Religion, Science and Ethics. From Antiquity to Modernity.” Presented for Ideas Club, Houston, July 27, 2014.
Seminar : “What Does Modern Science Say about the Origin of Human Moral Behavior? Science Confirms Philosophy.” Research Week, Texas Southern University, Houston, April 2, 2015.
Seminar for Humanists of Houston: “How the Struggle for Freedom of Conscience and Separation of State and Religion was Won in the West. A Study in the History of Freedom of Conscience.” Houston, September 18, 2015.
Seminar for Ideas Club, Humanists of Houston: “Science and Morality”, Houston, November 14, 2015.
Paper “Modern Science Explains Natural Moral Law Postulated by Philosophers.” Presented at the 14th Annual Hawaii International Conference on Arts and Humanities, Honolulu, Hawaii, January 9 – 12, 2016.
Presentation “The Role of the Polish Socinians for the Development of American Constitution and Democracy” given for The Polish Institute of History, Polish Academy of Science, Warsaw, February 22, 2016.
Research
The Center offers opportunity for students in Humanities at Texas Southern University to engage in research leading to their M.A. and /or Ph.D. thesis/dissertation.
We solicit participation of interested students for research in the areas of interest to the Center as well as we invite other faculties at Texas Southern University for a collaborative work.
Dale, Zuri
Education and Training
B.S. Texas Southern University Biology May 2011-Cum Laude
Texas A&M University MWM Water Mgmt. &Hydrological Sciences August 2014
Biography
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Research Interests
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Funding
Hispanic Leaders in Agriculture and the Environment Fellow, Texas A&M University
Bridge to Doctorate Fellow, Texas A&M University 2011-2013: 30,000/year and 9,000/year tuition assistance
Williams, Warren
Education and Training
Cellular and Molecular Biology – Ph.D. University of Illinois ; 1975 Urbana, Illinois
Developmental Biology M.S. – Texas Southern University; 1969
Biology B.S. – Texas Southern University; 1967
Biography
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Research Interests
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Research/Scholarly Activities
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Recent Publications
Williams , W.E. and J.W. Drake; Mutagenesis in Bacteriophage T4. American Society for Microbiology 104:218.
Williams, Warren E. and John W. Drake. Mutator Mutations in Bacteriophage T4 Gene 42 (dHMC Hydroxymethylase)
Funding
Studies into the Mechanism of Action of the Bacteriophage T4 Gene 42 Protein Product. TSU; 1975 1976; $4,000.00
The Mechanism of Action of the Bacteriophage T4 Gene 42 Product. Division of Research Resources, National Institutes of Health; 1976 1992. $579,400.00.
Sundaresan, Alamelu
Education and Training
Ph.D. in Environmental Sciences and Molecular Pathology, University of Texas Health Science Center in Houston.
M.Sc. in Medical Entomology, Vector Control research Center (WHO), Pondicherry, India.
B.S. in Zoology, Women’s Christian College, Chennai, India.
Research Interests
Expression of key immune changes under immune suppressed conditions such as microgravity and cancer,
Development of three-dimensional human tissue engineering models using no scaffolds.
Signaling mechanisms involving the gut-brain axis in inflammation, nano-formulation, nanotechnology and mathematical radiation tissue modeling of heavy ion effects.
Nutritional immunomodulation
Research Grants (since 2007)
“Center for Biomedical and Minority Institutions Program”, NIH/NIMHD-Research Centers in Minority Institutions Program (RCMI), U54MD007605, $8,632,113, 2020-2025, Role: Faculty Expert
Somatic hypermutation of B cells in Microgravity-NASA Space Biology program, $180603.00, 2020-2023, Role PI
NSF Targeted Infusion Program 1929976 Sundaresan, (PI) 06/01/2019-05/31/2021 $66414
PI: Gene expression and transcriptomics of ETAS Effects in an APP murine model. Funded by Amino Up Chemical, Jan 1-Dec 31, 2018-Dec 31, 2020. $30,316.00
PI: NSF “Targeted Infusion Project: Establishment of an Undergraduate Peer-Mentor Project-Based Program in STEM at Texas Southern University,” June 1, 2017 -May 31, 2021, $393,985.00.
PI: Studies of marker and chemo-microcapsules in normal and breast tumor cells”. Nu Vue Therapeutics, Feb 1, 2015-March 31, 2016 ($55,000.00+$50000.00). December 31, 2016-2018.
PI: Subcontract agreement between SAIC (Science Applications International Corporation NASA and TSU. May 18, 2015-September 30, 2016 ($25,691.20).
PI: Mickey Leland Faculty led -Study Abroad grant from Texas Southern University-Awarded January 2015,2016 – ($ 5000.00).
PI: NASA Johnson Space Center (JSC) International Space Station (ISS) University Research Project. The effect of benzofuran 2-carboxylic acid derivatives in the augmentation of the immune system (UR-1)- 2013-2015 (1.67 million). TSU lead over five other HBCUs.
PI: Effects of AHCC in human lymphocytes in modeled microgravity. Pilot grant from Amino Up Chemical Company, Japan March 2013-August 2015($25,000.00), Second award-$10000.00. Contract (March 1 2016-April 30, 2018)
PI: The effect of UV radiation on skin fibroblasts in parabolic flight and microgravity: National Space Grant Foundation, 2013 ($5000.00).
PI-Development and elucidation of technologies to mitigate bone loss in microgravity: UNCSFP-NASA grant awarded 2011. Grant period 2011-2014 ($600,000.00).
PI: Toxicological studies of Lunar dust in three-dimensional lung tissue models; NASA grant, awarded, 2010-2011($50,000.00)
Co-Principal Investigator:D.Das/Dr.Alamelu Sundaresan. Modelling ‘in vitro’ cell culture under microgravity conditions using NASA’s rotating bioreactor. Travel Grant to invite scientists from abroad, the Royal Society, UK. 2010 (15000.00 pounds sterling).
PI: NASA Administrator’s Fellowship Program (NAFP) FAR research endeavor: Awarded July, 2008-2010 with matching NASA funds ($75,000.00).
Principal Investigator: NASA administrator’s Grant: Awarded from 2007-2009 ($200,000)
Selected Awards and Honors
European Low Gravity Research Association-Life Sciences “Collaboration with Europe “Lifetime achievement award, September, 2019 in Granada Spain.
Scholarly Research and Creative activities award at Texas Southern University –May 2019, Dr. Sundaresan.
Dr. Sundaresan. Deutsche Welle radio interview on the Spectrum program in honor of Women’s day (March 8th 2018). Topic: Where are all the women in science? SoundCloud: https://soundcloud.com/deutsche-welle-in-english/spectrum-where-are-all- the-women-in-science
DW Media Center: http://www.dw.com/en/spectrum-where-are-all-the-women-in- science/av-42846358
Student Opportunities in Airborne Research (SOAR) on NASA’s WB-57 High Altitude Aircraft. (PI: Dr. Sundaresan, CO PI: Vivek Mann, Elvis Okoro)
Women in Scientific Excellence Award in Texas, July 2015:
Johnson Space Center- NASA University Research 1 project Group Achievement Award- January 2015(Principal Investigator)
Speaker at DLR: https://www.dlr.de/me/en/desktopdefault.aspx/tabid-1752/2384_read- 46684/
Speaker-University of Oslo.https://www.odont.uio.no/forskning/aktuelt/arrangementer/gjesteforelesninger/alamelu_o pt.html
Best Research Award: July 2014, 2016 for The International Congress on Nutrition and Integrative Medicine (ICNIM) for the project “AHCC Triggers Immune Proliferation and Activation of Human Lymphocytes via Targeted Phenotypic and Genotypic Transformation”.-July, 2014.
Deans leadership Award-June 2011
COURSES: Head professor for Anatomy and Physiology
Biol 135: Human Anatomy and Physiology Pre-Nursing Part 1(3 credit hours)
Biol 136: Human Anatomy and Physiology Pre-Nursing Part 2(3 credit hours)
Biol 245: Comprehensive Human Anatomy and Physiology-One semester course (3 credit hours)
Publications
TT Le, A Ropars, A Sundaresan, B Crucian, A Choukér, JP Frippiat.Pharmacological Countermeasures to Spaceflight-Induced Alterations of theImmune System. Stress Challenges and Immunity in Space, 637-657, 2020.
Vivek Mann, Alamelu Sundaresan, Satish Mehta, Brian Crucian, Sundar Devakottai. Effects of microgravity and other space stressors in immunosuppression and viral reactivation with potential nervous system involvement. Neurology India, 67 (8), 198.May 2019.
V Mann, A Sundaresan, M Chaganti.Cellular changes in the nervous system when exposed to gravitational variation.Neurology India 67 (3), 684, August 2019.
Z Peng, A Sundaresan, D Bick, S Umar, MF Doursout. Role of the Microbiome on the Modulation of the Intestinal Barrier in LPS Rats. The FASEB Journal 33 (1_supplement), lb65-lb65, 2019.
Vivek Mann , Daniela Grimm , Thomas J Corydon , Marcus Krüger, Markus Wehland, Stefan Riwaldt , Jayashree Sahana, Sascha Kopp, Johann Bauer, Janne E. Reseland, Manfred Infanger, Aina Mari Lian , Elvis Okoro and Alamelu Sundaresan 1, . Changes in Human Foetal Osteoblasts Exposed to the Random Positioning Machine and Bone Construct Tissue Engineering. J. Mol. Sci.2019, 20(6), 1357; https://doi.org/10.3390/ijms20061357 (registering DOI)
Vivek Mann, Elvis Okoro, Ayodotun Sodipe, Courtney Williams, Patricia Ngantcha and Alamelu Sundaresan. Lymphocyte Signaling and Function in Altered Physiological Environments. Published: December 17th 2018. DOI: 10.5772/intechopen.81171
Anil D Kulkarni, Marie-Francoise Doursout, Asmita Kulkarni, Alamelu Sundaresan, Takehito Miura, Koji Wakame and Hajime Fujii. Spaceflight: Immune Effects and Nutritional Countermeasure. Published: May 30th 2018.DOI: 10.5772/intechopen.74709
Sigrid Haugen,1 Jianying He,2 Alamelu Sundaresan,3 Astrid Kamilla Stunes,4,5 Kristin Matre Aasarød,4,5 Hanna Tiainen,1 Unni Syversen,4,6 Bjørn Skallerud,2 and Janne Elin Reseland1,* Adiponectin Reduces Bone Stiffness: Verified in a Three-Dimensional Artificial Human Bone Model In Vitro. Front Endocrinol (Lausanne). 2018; 9: 236.
Okoro E, Mann V, Ellis I, Mansoor E, Olamigoke L, Marriott KC, Denkins P, Williams W, Sundaresan A. Immune modulation in normal human peripheral blood mononuclear cells (PBMCs) (Lymphocytes) in response to benzofuran-2- carboxylic acid derivative KMEG during spaceflight. Microgravity Science and Technology. 2017 August; 29(4): 331-336. DOI: 10.1007/s12217-017-9551-z.
Sundaresan A, Mehta S.K, Schlegel T.T., Russomano T, Pierson D.L, Mann V, Olamigoke L, Mansoor E, Okoro E. Placental Growth Factor Levels in Populations with High Versus Low Risk for Cardiovascular Disease and Stressful Physiological Environments such as Microgravity: A Pilot Study: Placental growth factor levels in cardiac disease. Microgravity science and technology. 2017 February 02; 1-5.
Doursout MF, Liang Y, Sundaresan A, Wakame K, Fujii H, Takanari J, Devakottai S, Kulkarni A. Active hexose correlated compound modulates LPS- induced hypotension and gut injury in rats. Int Immunopharmacol. 2016 Aug 5;39:280-286. doi: 10.1016/j.intimp.2016.07.023. [Epub ahead of print]
Neal R. Pellis · Alexander Chouker · B. Yic · Svantje Tauber · Oliver Ullrich · Sundaresan. Overview and Translational Impact of Space Cell Biology Research. Chapter · December 2015.DOI: 10.1007/978-1-4939-3277-1_1 In book: Effect of Spaceflight and Spaceflight Analogue Culture on Human and Microbial Cells, pp.3-37. http://www.springer.com/us/book/9781493932764
Grimm, J,Grosse, V.Mann, J.E.Reseland, A.Sundaresan and T.Corydon, The impact of microgravity on bone. Bone. Vol 87, pages 44-56, June 2016.
Thomas J. Corydona Vivek Mann, Lasse Slumstrup, Sascha Kopp,Jayashree Sahana, Anne Louise Askou, Nils E. Magnusson David Echegoyen, Toke Bek Alamelu Sundaresan, Stefan Riwaldta, Johann Bauerf, Manfred Infangerand Daniela Grimm. .Reduced Expression of Cytoskeletal and Extracellular Matrix Genes in Human Adult Retinal Pigment Epithelium Cells Exposed to Simulated Microgravity. Cell Physiol Biochem 2016;40:1-17.
Olamigoke L, Mansoor E, Mann V, Ellis I, Okoro E, Wakame K, Fuji H, Kulkarni A, Francoise Doursout M, Sundaresan A.AHCC Activation and Selection of Human Lymphocytes via Genotypic and Phenotypic Changes to an Adherent Cell Type: A Possible Novel Mechanism of T Cell Activation. Evid Based Complement Alternat Med. 2015;2015:508746. doi: 10.1155/2015/508746. Epub 2015 Dec 15.PMID: 26788109 Free PMC Article.
Kogiso M, Wakame K, Sakai T, Yamamoto S, Sundaresan A, Kulkarni AD*Active Hexose Correlated Compound and T cell Response in Hind – Limb – Unloaded BALB/c Mice. International Journal of Surgery and Research (IJSR) / IJSR-2379-156X-02-501 9Dec 2015) .
Sundaresan, K. Marriott, J. Mao, S. Bhuiyan, and P. Denkins. The effects of benzofuran-2-carboxylic acid derivatives as countermeasures in immune modulation and cancer cell inhibition.. Microgravity Sci. Technol. (2015) 27:129– 140.
laboratory investigates the effect of autophagy modulation on the sensitivity of cancer cells to anticancer therapy. Using lenitvirus, we have generated several stable knockdown cancer cell lines that have enabled the laboratory to investigate the effect of autophagy proteins on the response of cancer cells to anticancer drug treatment. We have shown that autophagy inhibition, through knockdown of ATG5, can have an opposing effect on osteosarcoma cells treated with camptothecin. We are currently investigating the mechanisms responsible for this opposing effect. We are also investigating the effect of other autophagy-related proteins on the response of cancer cells to anticancer drug treatment.
The laboratory also investigates cell death signaling pathways in cancer cells. Here, we also use lentivirus to knockdown the expression of select cell death pathway-associated proteins to better understand their role in the cell death pathway. In addition, the laboratory also investigates the role of endogenous antioxidants in protecting cancer cells against anticancer drug-induced cytotoxicity.
