COLLEGE OF SCIENCE,
ENGINEERING AND
TECHNOLOGY
Assistant Professor
SB 203-E | (713) 313.7784
hollomon_mg@tsu.edu
Curriculum Vitae

Education and Training

  • B.S., Biological Sciences, Prairie View A&M University, 1993
  • M.S., Environmental Toxicology, Texas Southern University, 1997
  • Ph.D., Environmental Toxicology, Texas Southern University, 2003

POSTDOCTORAL TRAINING:

  • Department of Immunology – The University of Texas MD Anderson Cancer Center, Houston, TX 2005 2007
  • Department of Experimental Pediatrics – The University of Texas MD Anderson Cancer Center Houston, TX 2007 2011

HONORS AND AWARDS:

  • University Academic Scholarship Prairie View A&M University, 1987
  • Premedical Concepts Institute Scholarship Prairie View A&M University, 1987
  • Department of Biology Scholar Prairie View A&M University, 1992
  • EPA Predoctoral Fellowship, $75,000, 1997-2000
  • National Heart, Lung and Blood Institute (NHLBI) traineeship recipient (did not accept), 2001
  • Whos Who Among Americas Teachers, 2001
  • National Heart, Lung and Blood Institute (NHLBI) Postdoctoral Fellowship, 2005
  • National Cancer Institute (NCI) Postdoctoral Fellowship, 2007
  • Mike Doiron Memorial 19th Annual Legends of Friendswood Education Foundation Award, The University of Texas M. D. Anderson Cancer Center and The Legends of Friendswood Education Foundation, $15,000, 2008
  • National Cancer Institute (NCI) Postdoctoral Fellowship, 2010

PROFESSIONAL MEMBERSHIPS:

  • American College of Toxicology (ACT)
  • Beta Kappa Chi National Scientific Honor Society
  • Society of Environmental Toxicology and Chemistry (SETAC)
  • National Organization for the Professional Advancement of Black Chemists and Chemical Engineers (NOBCChE)

Research/Scholarly Activities

  • SDS-PAGE
  • Immunohistochemistry
  • Spectrophotometry
  • Immunoprecipitation
  • ELISA
  • Immunofluorescence
  • Flow cytometry/FACS analysis
  • Cell death assays
  • Cell culture
  • Cell isolation and purification
  • Generation of plasmid DNA
  • DNA and RNA purification
  • Experimental design preparation
  • Animal care and genotyping
  • Polymerase Chain Reaction (PCR)
  • Bacterial transformation
  • Cell transfection and transduction
  • Primary cell line generation
  • Murine bone marrow transplant
  • Murine embryo harvesting and dissection
  • Animal handling and dissection
  • Numerous other standard laboratory techniques

Recent Publications (out of a total of xxx)

  • Yu L, Su B, Hollomon M, Facchinetti V, Zhou Z, Kleinerman E. The use of MEKK3 knockout bone marrow cells to demonstrate the essential role of vasculogenesis in Ewings sarcoma growth. Cancer Res 2010, 70:1334-1343.
  • Huang G, Yu L, Cooper L, Hollomon M, Huls H, Kleinerman E. Genetically modified T cells targeting interleukin-11 receptor I^+–chain kill human osteosarcoma cells and induce the regression of established osteosarcoma lung metastases. Cancer Res 2012, 72(1):271-281.
  • Hollomon M,1,2 Santiago-OFarrill JM,1 Kleinerman E.1 Knockdown of essential protein, ATG5, decreases oxidative stress and has an opposing effect on camptothecin-induced cytotoxicity in osteosarcoma cells. [submitted under review (abstract available for preview)]
    1Childrens Cancer Hospital of MD Anderson Cancer Center, Houston, TX
    2 Texas Southern University, Department of Biology, Houston, TX
  • Hollomon M,1,2 Zhou Z,1 Santiago-OFarrill JM,1 Gordon N,1 Kleinerman E.1 Fas-associated protein with Death Domain (FADD) knockdown sensitizes osteosarcoma to TNF-induced cell death. [submitted under review (abstract available for preview)] 1Childrens Cancer Hospital of MD Anderson Cancer Center, Houston, TX
    2 Texas Southern University, Department of Biology, Houston, TX
  • Nishimoto K,1 Yang Y,1 Hollomon M,1,2 Bernard V, Hughes D,1 Kleinerman E.1 MS-275 increases Fas expression on osteosarcoma cells by a mechanism involving the microRNA-17-92 cluster and E2F1 transcription. [expected submission in August]
    1Childrens Cancer Hospital of MD Anderson Cancer Center, Houston, TX
    2 Texas Southern University, Department of Biology, Houston, TX
  • Gordon, N,1 Hsuan-Chu C,1 Santiago OFarrell, J,1 Gilbert, B,1 Hollomon, M,1,2 Kleinerman, E.1 The microenvironment plays an important role in the ability of aerosol Liposomal
    9-Nitorcamptothecin and Gemcitabine to elicit therapeutic effect on Osteosarcoma lung metastases. [in preparation]
    1Childrens Cancer Hospital of MD Anderson Cancer Center, Houston, TX
    2 Texas Southern University, Department of Biology, Houston, TX

ABSTRACTS AND OTHER PRESENTATIONS:

  • Department of Experimental Pediatrics, The University of Texas MD Anderson Cancer Center, 9-nitrocamptothecin-induced Autophagy in Osteosarcoma Cells March 18, 2008
  • Autophagy in Health and Disease: A Workshop on Cross-Disciplinary Issues, The University of Texas Medical School at Houston, Camptothecin-induced Autophagy November 14, 2008
  • Department of Cancer Biology Seminar Series, The University of Texas MD Anderson Cancer Center, 9-nitrocamptothecin-induced Autophagy in Osteosarcoma Cells January 21, 2009
  • Department of Experimental Pediatrics, The University of Texas MD Anderson Cancer Center, Autophagy Induction in Osteosarcoma May 12, 2009
  • Department of Experimental Pediatrics, The University of Texas MD Anderson Cancer Center, Drug-induced Autophagy in Osteosarcoma March 9, 2010

Funding

  • Texas Southern University – University Seed Grant
    Hogan (PI) Hollomon (Co-PI), 2003
    [grant written by Hollomon]
  • National Heart Lung and Blood Institute (National Institutes of Health)
    Research supplement grant 7R011HL070225-03S1 (PI- Su)
    Funds awarded to support Postdoctoral studies for Mario Hollomon, Ph.D.
    (2005-2007, $119,596)
    [grant written by Su]
  • National Cancer Institute (National Institutes of Health)
    Research supplement grant 5R01CA042992-22S1 (PI Kleinerman)
    Funds awarded to support Postdoctoral studies for Mario Hollomon, Ph.D.
    (2007-2009, $213,803)
    [grant written by Hollomon]
  • National Cancer Institute (National Institutes of Health)
    Research supplement grant 5R01CA042992-24S1 (PI Kleinerman)
    Funds awarded to support Postdoctoral studies for Mario Hollomon, Ph.D.
    (2010-2011, $92,714)
    [grant written by Hollomon]